merck millipore,默克密理愽
  • merck millipore,默克密理博,573128,STAT3 Inhibitor XIII, C188-9 - Calbiochem

  • merck millipore,默克密理博,573128,STAT3 Inhibitor XIII, C188-9 - Calbiochem

    产品名称：STAT3 Inhibitor XIII, C188-9 - Calbiochem
    产品型号：573128
    The Stat3 Inhibitor XIII, C188-9 controls the biological activity of Stat3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,573128,STAT3 Inhibitor XIII, C188-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,573128,STAT3 Inhibitor XIII, C188-9 - Calbiochem

    重要规格表

    经验配方
    C₂₇H₂₁NO₅S
    描述
    概述 A cell-permeable binaphthol-sulfonamide that competes against pY proteins for Stat3 SH2 domain binding. Shown to inhibit G-CSF-induced Stat3 tyr705 phosphorylation in human AML cell lines and primary cultures (IC50 from 4.1 to 18 µM). Also shown to inhibit G-CSF-stimulated TIE2, MATK, JAK1, and HGFR phosphorylation (by 90%, 50%, 40%, and 40%, respectively; 10 µM C188-9), but not 15 other phosphoproteins (≤30% inhibition), including pERK1/2 and pAKT, in Kasumi-1 cells.
    产品目录编号 573128
    品牌系列 Calbiochem®
    同义词 N-(1ʹ,2-Dihydroxy-1,2ʹ-binaphthalen-4ʹ-yl)-4-methoxybenzenesulfonamide, F1113-0789
    参考
    参考 Redell, M.S., et al. 2011. Blood 112, 355.
    产品信息
    形式 Off-white to pale beige powder
    Hill配方 C₂₇H₂₁NO₅S
    化学配方 C₂₇H₂₁NO₅S
    Molar Mass 471.5
    结构配方图像
    生物信息
    纯度 ≥98% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Toxic
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,573128,STAT3 Inhibitor XIII, C188-9 - Calbiochem

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