merck millipore,默克密理愽
  • merck millipore,默克密理博,573126,STAT3 Inhibitor XI, STX-0119 - Calbiochem

  • merck millipore,默克密理博,573126,STAT3 Inhibitor XI, STX-0119 - Calbiochem

    产品名称：STAT3 Inhibitor XI, STX-0119 - Calbiochem
    产品型号：573126
    The STAT3 Inhibitor XI, STX-0119 controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,573126,STAT3 Inhibitor XI, STX-0119 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,573126,STAT3 Inhibitor XI, STX-0119 - Calbiochem

    重要规格表

    经验配方
    C₂₂H₁₄N₄O₃
    描述
    概述 A cell-permeable oxadiazolyl-quinolinecarboxamide that is shown to selectively suppress STAT3, but not STAT1, STAT5a, or STAT5b, DNA binding activity and prevent IL-6-stimulated STAT3 dimerization in HEK293 cells (by 99% at 100 µM), as well as inhibit the expression of STAT3 target genes both in cultures in vitro (effective conc. 50 µM) and in SCC3-derived tumors in mice in vivo (160 mg/kg/day; p.o.).
    产品目录编号 573126
    品牌系列 Calbiochem®
    同义词 N-(5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl)-2-phenylquinoline-4-carboxamide
    参考
    参考 Ashizawa, T., et al. 2011. Int. J. Oncol. 38, 1245,
    Matsuno, K., et al. 2010. ACS Med. Chem. Lett. 1, 371.
    产品信息
    形式 Greyish to off-white solid
    Hill配方 C₂₂H₁₄N₄O₃
    化学配方 C₂₂H₁₄N₄O₃
    Molar Mass 382.4
    结构配方图像
    生物信息
    纯度 ≥90% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,573126,STAT3 Inhibitor XI, STX-0119 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,182516,Arp2/3 Complex Inhibitor II, CK-869 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,567806,Src Kinase Inhibitor II - CAS 459848-35-2 - Calbiochem


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