merck millipore,默克密理愽
  • merck millipore,默克密理博,565780,β-Secretase Inhibitor III - Calbiochem

  • merck millipore,默克密理博,565780,β-Secretase Inhibitor III - Calbiochem

    产品名称：β-Secretase Inhibitor III - Calbiochem
    产品型号：565780
    The β-Secretase Inhibitor III controls the biological activity of β-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.

    merck millipore,默克密理博,565780,β-Secretase Inhibitor III - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,565780,β-Secretase Inhibitor III - Calbiochem

    重要规格表

    经验配方
    C₄₄H₇₀N₁₀O₁₄
    描述
    概述 A substrate analog inhibitor of β-secretase (BACE) that completely blocks the proteolytic activity (at 5 µM) in solubilized membrane fractions from BACE transfected MDCK cells.
    产品目录编号 565780
    品牌系列 Calbiochem®
    同义词 Inhibitor GL189, H-EVNstatineVAEF-NH₂
    参考
    参考 Capell, A., et al. 2002. J. Biol. Chem. 277, 5637.
    Tung, J.S., et al. 2002. J. Med. Chem. 45, 259.
    产品信息
    具有ATP竞争性 N
    形式 Lyophilized
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₄₄H₇₀N₁₀O₁₄
    化学配方 C₄₄H₇₀N₁₀O₁₄
    Molar Mass 963.1
    吸湿 Hygroscopic
    肽序列 H-Glu-Val-Asn-Statine-Val-Ala-Glu-Phe-NH₂
    可逆 N
    生物信息
    主靶 BACE
    主靶IC50 Effective concentration: 5 µM completely blocking the proteolytic activity of β-secretase (BACE) in solubilized membrane fractions from BACE transfected MDCK cells
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    肽序列 H-Glu-Val-Asn-Statine-Val-Ala-Glu-Phe-NH₂
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,565780,β-Secretase Inhibitor III - Calbiochem

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