merck millipore,默克密理博,04-418,Anti-phospho-p90 RSK1 (Ser380) Antibody, rabbit monoclonal

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merck millipore,默克密理博,04-418,Anti-phospho-p90 RSK1 (Ser380) Antibody, rabbit monoclonal
产品名称：Anti-phospho-p90 RSK1 (Ser380) Antibody, rabbit monoclonal
产品型号：04-418
Anti-phospho-p90 RSK1 (Ser380) Antibody, Rabbit detects level of phospho-p90 RSK1 (Ser380) & has been published & validated for use in IF, IP & WB.

merck millipore,默克密理博,04-418,Anti-phospho-p90 RSK1 (Ser380) Antibody, rabbit monoclonal

产品介绍

merck millipore,默克密理博,04-418,Anti-phospho-p90 RSK1 (Ser380) Antibody, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	WB	Rb	Purified	Monoclonal Antibody

描述
产品目录编号	04-418
品牌系列	Upstate
商名	Upstate
描述	Anti-phospho-p90 RSK1 (Ser380) Antibody, rabbit monoclonal
Alternate Names	RPS6KA1, MAPKAPK1A, RSK, RSK1, S6K-alpha 1, ribosomal protein S6 kinase, 90kDa, polypeptide 1 90kDa ribosomal protein S6 kinase S6K-alpha 1 RSK1 RSK MAPKAPK1A RPS6KA1

产品信息
格式	Purified
演示	100 μL of rabbit monoclonal IgG in 30 mM Tris-Glycine (pH 7.4), 90 mM NaCl, 0.006% sodium azide, 0.03% BSA and 40% glycerol.

应用
应用	Anti-phospho-p90 RSK1 (Ser380) Antibody, Rabbit detects level of phospho-p90 RSK1 (Ser380) & has been published & validated for use in IF, IP & WB.
主要应用	Western Blotting
应用说明	Suggested Dilutions: Immunoblot Analysis: 1:10,000 Immunoprecipitation: 1:250 - 1:500 Immunfluorescence Staining: 1:50

生物信息
免疫原品种	KLH-conjugated synthetic peptide corresponding to serine 380 and surrounding amino acids of human p90 RSK-1.
宿主	Rabbit
特异性	Recognizes Rsk-1 when phosphorylated on Ser380.
同种型	IgG
品种反应性	RatHumanMouse
抗体类型	Monoclonal Antibody
Entrez基因编号	NM_002953.3 NM_001006665.1
Entrez基因汇总	This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
基因符号	RSK1 RPS6KA1 HU-1 RSK-1 MAPKAPK1A RSK pp90RSK1 p90S6K
修改	Phosphorylation
UniProt编号	Q15418
UniProt汇总	FUNCTION: SwissProt: Q15418 # Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB. COFACTOR: Magnesium. SIZE: 735 amino acids; 82723 Da SUBUNIT: Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation. PTM: Autophosphorylated on Ser-380, as part of the activation process. SIMILARITY: SwissProt: Q15418 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 protein kinase domains.

产品使用声明
质量保证	Routinely evaluated by immunoblot.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.

储存和货运信息

存储条件

2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.