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品种反应性 主要应用 宿主 格式 抗体类型 H WB, IHC Rb Serum Polyclonal Antibody 描述 产品目录编号 ABC509 描述 Anti-DEK Antibody Alternate Names - Protein DEK
背景信息 DEK, also known as Protein DEK, and encoded by the gene DEK, is a human chromatin modification protein found in mRNA splicing-dependent complexes. DEK interacts with histones and other chromatin proteins and is a component of the B-WICH complex, a critical complex needed for proper transcription of the 5S rRNA genes and 7SL genes by RNA polymerase III which is necessary for cell growth and proliferation. DEK protein also plays an important role in cell apoptosis and high expression levels of the human DEK have been correlated with numerous human malignancies. DEK localizes to the nucleus and has been shown to be an effective biomarker in the progression of colorectal cancers. 产品信息 格式 Serum 演示 Rabbit polyclonal serum with 0.05% sodium azide. 应用 应用 Anti-DEK Antibody detects level of DEK & has been published & validated for use in DEK. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Immunohistochemistry Analysis: A representative lot detected DEK in human melanoma tissue (Khodadoust, M., et al. (2009). Cancer Res. 69:6405-6413). 生物信息 免疫原品种 Recombinant protein corresponding to human DEK. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001128181
基因符号 - DEK
纯化方法 Unpurified UniProt编号 - P35659
产品使用声明 质量保证 Evaluated by Western Blotting in Jurkat cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected DEK in 10 µg of Jurkat cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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