merck millipore,默克密理愽
  • merck millipore,默克密理博,557525,Ro-32-0432 - CAS 145333-02-4 - Calbiochem

  • merck millipore,默克密理博,557525,Ro-32-0432 - CAS 145333-02-4 - Calbiochem

    产品名称：Ro-32-0432 - CAS 145333-02-4 - Calbiochem
    产品型号：557525
    A selective cell-permeable protein kinase C inhibitor.

    merck millipore,默克密理博,557525,Ro-32-0432 - CAS 145333-02-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,557525,Ro-32-0432 - CAS 145333-02-4 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₈H₂₈N₄O₂ · HCl145333-02-4
    描述
    概述 A selective cell-permeable protein kinase C inhibitor. Displays about 10-fold greater selectivity for PKCα (IC50 = 9 nM) and 4-fold greater selectivity for PKCβI (IC50 = 28 nM) over PKCε (IC50 = 108 nM). Also prevents T cell-driven chronic inflammatory responses in vivo.

    Please note that the molecular weight for this compound is batch-specific due to variable water content.
    产品目录编号 557525
    品牌系列 Calbiochem®
    同义词 2-{8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-3-yl}-3-(1-methyl-1H-indol-3-yl)maleimide, HCl, Bisindolylmaleimide XI, HCl, 3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-y1)-4-(1-methyl-1H-indol-3-y1)-1H-pyrrole-2,5-dione hydrochloride
    参考
    参考 Birchall, A.M., et al. 1994. J. Pharmacol. Exp. Ther. 268, 922.
    Wilkinson, S.E., et al. 1993. Biochem. J. 294, 335.
    产品信息
    CAS号 145333-02-4
    具有ATP竞争性 N
    形式 Red solid
    Hill配方 C₂₈H₂₈N₄O₂ · HCl
    化学配方 C₂₈H₂₈N₄O₂ · HCl
    可逆 N
    结构配方图像
    生物信息
    主靶 PKCα
    主靶IC50 9 nM, 28 nM, 108 nM, against PKCα, PKCβI, and PKCε, respectively
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

    merck millipore,默克密理博,557525,Ro-32-0432 - CAS 145333-02-4 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,5980-OP,OmniPur Magnesium Chloride, Hexahydrate - CAS 7791-18-6 - Calbiochem
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