merck millipore,默克密理愽
  • merck millipore,默克密理博,528281,Polo-like Kinase Inhibitor IV, SBE13 - CAS 775294-82-1 - Calbiochem

  • merck millipore,默克密理博,528281,Polo-like Kinase Inhibitor IV, SBE13 - CAS 775294-82-1 - Calbiochem

    产品名称：Polo-like Kinase Inhibitor IV, SBE13 - CAS 775294-82-1 - Calbiochem
    产品型号：528281
    The Polo-like Kinase Inhibitor IV, SBE13, also referenced under CAS 775294-82-1, controls the biological activity of Polo-like Kinase. This small molecule/inhibitor is primarily used for Phosphorylati More>>

    merck millipore,默克密理博,528281,Polo-like Kinase Inhibitor IV, SBE13 - CAS 775294-82-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,528281,Polo-like Kinase Inhibitor IV, SBE13 - CAS 775294-82-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₄H₂₇ClN₂O₄775294-82-1
    描述
    概述 A cell-permeable vanillin-derived pyridyl-ethanamine compound that acts as a highly potent type II Plk1 inhibitor (IC50 of 200 pM) and targets the less conserved DFG motif that is only accessible when the kinase is in its inactive DFG-out conformation, resulting in an excellent selectivity over Plk2 (IC50 >66 µM), Plk3 (IC50 = 875 nM), and aurora A kinase (no detectable effect). Shown to inhibit the proliferation of HeLa cells with an EC50 of 18 µM.
    产品目录编号 528281
    品牌系列 Calbiochem®
    同义词 N-(4-((6-Chloro-3-pyridinyl)methoxy)-3-methoxybenzyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)amine
    参考
    参考 Keppner, S., et al. 2009. ChemMedChem. 4, 1806.
    产品信息
    CAS号 775294-82-1
    形式 Beige solid
    Hill配方 C₂₄H₂₇ClN₂O₄
    化学配方 C₂₄H₂₇ClN₂O₄
    Molar Mass 442.9
    结构配方图像
    生物信息
    纯度 ≥94% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,528281,Polo-like Kinase Inhibitor IV, SBE13 - CAS 775294-82-1 - Calbiochem

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