merck millipore,默克密理愽
  • merck millipore,默克密理博,416157,Isohelenin, Inula sp. - Calbiochem

  • merck millipore,默克密理博,416157,Isohelenin, Inula sp. - Calbiochem

    产品名称：Isohelenin, Inula sp. - Calbiochem
    产品型号：416157
    A cell-permeable sesquiterpene lactone with anti-inflammatory properties.

    merck millipore,默克密理博,416157,Isohelenin, Inula sp. - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,416157,Isohelenin, Inula sp. - Calbiochem

    重要规格表

    经验配方
    C₁₅H₂₀O₂
    描述
    概述 A cell-permeable sesquiterpene lactone with anti-inflammatory properties. Acts as a highly specific, potent, irreversible inhibitor of NF-κB activation that acts by preventing IκBα degradation. Does not affect the DNA binding activity of activated NF-κB, or inhibit p59fyn and Src kinase activities. Inhibits IL-8 gene expression in cultured human respiratory epithelium in vitro, and iNOS gene expression in cultured rat aortic smooth muscle cells. Offers protection against endotoxic shock in vivo.
    产品目录编号 416157
    品牌系列 Calbiochem®
    同义词 Isoalantolactone
    参考
    参考 Sheehan, M., et al. 2002. J. Endotoxin. Res. 8, 99.
    Mazor, R.L., et al. 2000. Cytokine 12, 239.
    Wong. H.R., and Menendez, I.Y., 1999. Biochem. Biophys. Res. Commun. 262, 375.
    Hehner, S.P., et al. 1998. J. Biol. Chem. 273, 1288.
    Bork, P.M., et al. 1997. FEBS Lett. 402, 85.
    产品信息
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₁₅H₂₀O₂
    化学配方 C₁₅H₂₀O₂
    Molar Mass 232.3
    可逆 N
    结构配方图像
    生物信息
    主靶 NF-κB activation
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Blue Ice Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,416157,Isohelenin, Inula sp. - Calbiochem

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