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  • merck millipore,默克密理博,AB5581-200UL,Anti-P2X7 Receptor Antibody, extracellular domain

  • merck millipore,默克密理博,AB5581-200UL,Anti-P2X7 Receptor Antibody, extracellular domain

    产品名称：Anti-P2X7 Receptor Antibody, extracellular domain
    产品型号：AB5581-200UL
    Anti-P2X7 Receptor Antibody, extracellular domain is an antibody against P2X7 Receptor for use in WB.

    merck millipore,默克密理博,AB5581-200UL,Anti-P2X7 Receptor Antibody, extracellular domain

  • 产品介绍
  • merck millipore,默克密理博,AB5581-200UL,Anti-P2X7 Receptor Antibody, extracellular domain

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5581-200UL
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-P2X7 Receptor Antibody, extracellular domain
    产品信息
    格式 Affinity Purified
    控制
    • Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). For negative control, preincubate 1 μg of purified peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
    演示 Affinity purified immunoglobulin. Lyophilized from PBS, pH 7.4, containing 1% BSA and 0.05% sodium azide. Reconstitute with 200 μL of sterile distilled water. Centrifuge antibody preparation before use (10,000 x g for 5 min).
    应用
    应用 Anti-P2X7 Receptor Antibody, extracellular domain is an antibody against P2X7 Receptor for use in WB.
    主要应用
    • Western Blotting
    应用说明 Western blotting: 1:200 using ECL on rat brain membranes.

    Flow cytometry, indirect: 5-10 μg antibody per 1x10E6 cells.

    Dilutions should be made using a carrier protein such as BSA (1-3%).

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Highly purified peptide corresponding to residues 136-152 of mouse P2X7 (Accession Q9Z1M0).
    表位 extracellular domain
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes P2X7, extracellular domain.
    品种反应性 RatHuman
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_002562.4
    Entrez基因汇总 The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay (NMD) criteria.
    基因符号
    • P2X7
    • P2RX7
    • MGC20089
    UniProt编号
    • Q99572
    UniProt汇总 FUNCTION: SwissProt: Q99572 # Receptor for ATP that acts as a ligand gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
    SIZE: 595 amino acids; 68559 Da
    SUBUNIT: Forms homo- or heteropolymers. Interacts with LAMA3, ITGB2, ACTB, ACTN4, SVIL, MPP3, HSPA1, HSPCB, HSPA8, PIK230 and PTPRB.
    SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
    PTM: Phosphorylation results in its inactivation.
    SIMILARITY: SwissProt: Q99572 ## Belongs to the P2X receptor family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain lyophilized material at -20°C for up to 6 months after date of receipt. After reconstitution maintain antibody and control peptide at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 200 µL

    merck millipore,默克密理博,AB5581-200UL,Anti-P2X7 Receptor Antibody, extracellular domain

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