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品种反应性 主要应用 宿主 格式 抗体类型 Ch, H IHC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB19013 Replaces AB1951 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Tenascin Antibody 产品信息 格式 Affinity Purified 控制 - Embryonic chicken brain
演示 Affinity Purified using immobilized chicken tenascin. Provided as a liquid in PBS, containing no preservatives. 应用 应用 Anti-Tenascin Antibody is an antibody against Tenascin for use in IH, IH(P). 主要应用 - Immunohistochemistry
应用说明 Function blocking
Western blot: Antibody recognizes a 220-240kDa band in reduced westerns; antibody reacts best with chicken, followed by human (100X less reactive). Mouse reactivity under reduced conditions is poor.
Immunohistochemistry: frozen and paraffin embedded tissues; citrate treatment useful for paraffin tissues.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Purified tenascin from embryonic chicken brain. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Reactive with tenascin from chicken and human by immunohistochemistry. Under reducing conditions, reactivity to chicken is approximately 100X greater than reactivity with human tenascin. Reactivity with mouse tenascin under reducing conditions is poor, but reacts with mouse in paraffin embedded sections. 品种反应性 ChickenHuman 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_002160.2
基因符号 - Cytotactin
- TNC
- Hexabrachion
- HXB
- GMEM
- TN
- Neuronectin
- Tenascin-C
- MGC167029
- JI
- TN-C
纯化方法 Immunoaffinity purified UniProt编号 - P24821
UniProt汇总 FUNCTION: SwissProt: P24821 # Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
SIZE: 2201 amino acids; 240866 Da
SUBUNIT: Homohexamer; disulfide-linked. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4.
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.
PTM: N-glycosylated (By similarity).
SIMILARITY: SwissProt: P24821 ## Belongs to the tenascin family. & Contains 15 EGF-like domains. & Contains 1 fibrinogen C-terminal domain. & Contains 15 fibronectin type-III domains.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 50 µg
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