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merck millipore,默克密理博,524611,PIKfyve Inhibitor - CAS 371942-69-7 - Calbiochem
产品名称：PIKfyve Inhibitor - CAS 371942-69-7 - Calbiochem
产品型号：524611
The PIKfyve Inhibitor, also referenced under CAS 371942-69-7, controls the biological activity of PIKfyve. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation appli More>>
merck millipore,默克密理博,524611,PIKfyve Inhibitor - CAS 371942-69-7 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₂₅H₂₁N₇O₃ 371942-69-7 描述 概述 A cell-permeable pyridofuropyrimidine compound that selectively inhibits mammalian type III PtdInsP kinase (IC50 = 33 nM and >5 µM using murine PIKfyve and yeast Fab1, respectively), while exhibiting much reduced activity against p110α (IC50 = 3.3 µM) and little activity against type IIγ PtdInsP kinase even at concentrations as high as 10 µM. Shown to block serum-induced PtdIns(3,5)P2 production in NIH3T3 cells (80% inhibition at 800 nM) and disrupt cellular endosomal transport in a reversible manner. 产品目录编号 524611 品牌系列 Calbiochem®
同义词 6-Amino-N-(3-(4-(4-morpholinyl)pyrido[3ʹ2ʹ:4,5]furo[3,2-d]pyrimidin-2-yl)phenyl)-3-pyridine carboxamide, PtdIns3P 5-KInase Inhibitor, YM201636 参考 参考 Jefferies, H.B.J., et al. 2008. EMBO Reports 9, 164. 产品信息 CAS号 371942-69-7 形式 White solid Hill配方 C₂₅H₂₁N₇O₃ 化学配方 C₂₅H₂₁N₇O₃ Molar Mass 467.5 结构配方图像 生物信息 纯度 ≥97% by HPLC 理化信息 溶解度 DMSO 安全信息 S相 S: 22-24/25
Do not breathe dust.
Avoid contact with skin and eyes.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
上一件merck millipore产品：merck millipore,默克密理博,ABN253,Anti-PTGDS Antibody
下一件merck millipore产品：merck millipore,默克密理博,203882,CR8, (S)-Isomer - CAS 1084893-56-0 - Calbiochem
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