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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Rhesus Macaque, H IHC, WB Rb Purified Polyclonal Antibody 描述 产品目录编号 ABN253 描述 Anti-PTGDS Antibody Alternate Names - PGDS2
- Prostaglandin-H2 D-isomerase
- Beta-trace protein
- Cerebrin-28
- Glutathione-independent PGD synthase
- Lipocalin-type prostaglandin-D synthase
- Prostaglandin-D2 synthase
- PGD2 synthase
- PGDS
背景信息 Prostaglandin-H2 D-isomerase (PTGDS), also known the Lipocalin-type prostaglandin-D synthase, catalyzes the conversion of PGH2 to PGD2. PTGDS serves both as a PGD2-synthesizing enzyme and as an extracellular transporter of various lipophilic small molecules. It is the only enzyme in the lipocalin type protein family, members of which mainly act as binding proteins. It has been shown to bind various small, lipophilic compounds such as retinoic acid, biliverdin, bilirubin, retinoic acid, and thyroid hormone and may act as a scavenger for harmful hydrophobic molecules. In cells it is localized in the endoplasm reticulum, golgi apparatus, cell membrane, and is also secreted. PTGDS is involved in several central nervous system functions, such as sedation, pain regulation and non-rapid eye movement sleep. It is suggested to be involved in development and maintenance of the blood-brain, blood-retina, and blood-aqueous humor barriers and may also play a role in maturation and maintenance of the central nervous system. 产品信息 格式 Purified 控制 - Human testis tissue lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect the PTGDS protein using this Anti-PTGDS validated for use in WB & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 1:100 dilution from a representative lot detected PTGDS in human pons/midbrain and human cardiac myocytes. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human PTGDS. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Rhesus MacaqueHuman Species Reactivity Note Demonstrated to react with Human. Predicted to react with Rhesus Macaque based on 100% sequence homology. Other homologies: Feline (92% sequence homology), Canine (83% sequence homology), Mouse (75% sequence homology), no homology to Rat detected. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_000945
基因符号 - PDS
- PTGDS
纯化方法 Protein A purified UniProt编号 - P41222
产品使用声明 质量保证 Evaluated by Western Blot in human testis tissue lysate.
Western Blot Analysis: 0.2 µg/mL of this antibody detected PTGDS in 10 µg of human testis tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,345810,G 418 Sulfate, Cell Culture Tested - CAS 108321-42-2 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,524611,PIKfyve Inhibitor - CAS 371942-69-7 - Calbiochem
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