• merck millipore,默克密理博,513030,PD 169316 - CAS 152121-53-4 - Calbiochem
  • merck millipore,默克密理博,513030,PD 169316 - CAS 152121-53-4 - Calbiochem

    产品名称:PD 169316 - CAS 152121-53-4 - Calbiochem
    产品型号:513030
    A potent, cell-permeable, reversible, competitive, and selective p38 MAP kinase inhibitor (IC₅₀ = 89 nM).

    merck millipore,默克密理博,513030,PD 169316 - CAS 152121-53-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,513030,PD 169316 - CAS 152121-53-4 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₀H₁₃FN₄O₂152121-53-4
    描述
    概述 A potent, cell-permeable, reversible, competitive, and selective p38 MAP kinase inhibitor (IC50 = 89 nM). Inhibition of p38 MAP kinase by PD 169316 blocks apoptosis induced by trophic factor withdrawal in non-neuronal and neuronal cell lines.
    产品目录编号 513030
    品牌系列 Calbiochem®
    同义词 4-(4-Fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole
    参考
    参考 Nath, R., et al. 2001. Cell Mol. Biol. Lett. 6, 173.
    Gallagher, T.F., et al. 1997. Bioorg. Med. Chem. 5, 49.
    Kummer, J.L., et al. 1997. J. Biol. Chem. 272, 20490.
    产品信息
    CAS号 152121-53-4
    具有ATP竞争性 Y
    形式 Orange-yellow solid
    Hill配方 C₂₀H₁₃FN₄O₂
    化学配方 C₂₀H₁₃FN₄O₂
    Molar Mass 360.3
    可逆 Y
    结构配方图像
    生物信息
    主靶 p38 MAP kinase
    主靶IC50 89 nM against p38 MAP kinase
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

    merck millipore,默克密理博,513030,PD 169316 - CAS 152121-53-4 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,16-243,Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6, Alexa Fluor 488
下一件merck millipore产品:merck millipore,默克密理博,HTS021RTA,Ready-to-Assay™ MC2 Melanocortin Receptor Frozen Cells



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