• merck millipore,默克密理博,492030,NS 2028 - CAS 204326-43-2 - Calbiochem
  • merck millipore,默克密理博,492030,NS 2028 - CAS 204326-43-2 - Calbiochem

    产品名称:NS 2028 - CAS 204326-43-2 - Calbiochem
    产品型号:492030
    Potent, specific, and irreversible inhibitor of soluble guanylyl cyclase.

    merck millipore,默克密理博,492030,NS 2028 - CAS 204326-43-2 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,492030,NS 2028 - CAS 204326-43-2 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₉H₅BrN₂O₃204326-43-2
    描述
    概述 Potent, specific, and irreversible inhibitor of soluble guanylyl cyclase (IC50 = 30 nM for basal and 200 nM for NO-stimulated enzyme activity; IC50 = 17 nM for S-nitrosoglutathione-enhanced soluble guanylyl cyclase activity in homogenates of mouse cerebellum).
    产品目录编号 492030
    品牌系列 Calbiochem®
    同义词 4H-8-Bromo-1,2,4-oxadiazolo(3,4-d)benz(b)(1,4)oxazin-1-one
    参考
    参考 Fleming, I., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 1123.
    Olesen, S.P., et al. 1998. Br. J. Pharmacol. 123, 299.
    产品信息
    CAS号 204326-43-2
    具有ATP竞争性 N
    形式 White to off-white solid
    Hill配方 C₉H₅BrN₂O₃
    化学配方 C₉H₅BrN₂O₃
    Molar Mass 269.0
    可逆 N
    结构配方图像
    生物信息
    主靶 basal soluble guanylyl cyclase
    主靶IC50 30 nM for basal and 200 nM for NO-stimulated enzyme activity; 17 nM for S-nitrosoglutathione-enhanced soluble guanylyl cyclase activity in homogenates of mouse cerebellum
    纯度 ≥98% by NMR
    理化信息
    细胞可渗透 N
    溶解度 DMSO, EtOH, or CHCl₃
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    防潮 Protect from moisture
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C) for long-term storage. DMSO stock solutions are stable for up to 1 month at -20°C and for ~8 h at 4°C. Avoid freeze/thaw cycles of solutions.

    merck millipore,默克密理博,492030,NS 2028 - CAS 204326-43-2 - Calbiochem

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