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经验配方 CAS号 C₁₉H₂₆O₃ 362-07-2 描述 概述 A natural metabolite of 17β-estradiol that is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. Markedly inhibits the neovascularization of solid tumors and suppresses tumor growth in mice. Binds to the colchicine binding site of tubulin, and has been suggested to function as a natural regulator of microtubule assembly and function. 产品目录编号 454180 品牌系列 Calbiochem®
同义词 2-Methoxy-3,17β-dihydroxyestra-1,3,5(10)-triene 参考 参考 Aizu-Yokata, E., et al. 1995. Cancer Res. 55, 1863.
Cushman, M., et al. 1995. J. Med. Chem. 38, 2041.
D’Amato, R.J., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 3964.
Forsis, T., et al. 1994. Nature 368, 237.产品信息 CAS号 362-07-2 具有ATP竞争性 N 形式 White crystalline solid Hill配方 C₁₉H₂₆O₃ 化学配方 C₁₉H₂₆O₃ Molar Mass 302.4 可逆 N 结构配方图像 生物信息 主靶 Inhibits cell proliferation and angiogenesis 纯度 ≥90% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO or EtOH 安全信息 R相 R: 23/24/25-36/37/38
Toxic by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.S相 S: 22-26-36/37/39-45
Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).储存和货运信息 货运代码 Ambient Temperature Only
毒性 Toxic
有害材料注意事项： Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存 +15°C to +30°C
无需冷冻 No
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