• merck millipore,默克密理博,428206,Lck Inhibitor II - CAS 918870-43-6 - Calbiochem
  • merck millipore,默克密理博,428206,Lck Inhibitor II - CAS 918870-43-6 - Calbiochem

    产品名称:Lck Inhibitor II - CAS 918870-43-6 - Calbiochem
    产品型号:428206
    The Lck Inhibitor II, also referenced under CAS 918870-43-6, controls the biological activity of Lck. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicatio More>>

    merck millipore,默克密理博,428206,Lck Inhibitor II - CAS 918870-43-6 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,428206,Lck Inhibitor II - CAS 918870-43-6 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₄H₂₆N₆O₃918870-43-6
    描述
    概述 A cell-permeable, ATP binding site-targeting, tri-substituted pyrimidine that acts as a highly potent Lck (lymphocyte specific kinase) inhibitor (IC50 = 3 nM; [ATP] = 10 µM). Shown to block IL-2 release in Jurkat E6-1 T cell line (IC50 = 54 nM) stimulated by CD3 cross-linking and PMA.
    产品目录编号 428206
    品牌系列 Calbiochem®
    同义词 3-(2-(1H-Benzo[d]imidazol-1-yl)-6-(2-morpholinoethoxy)pyrimidin-4-ylamino)-4-methylphenol
    参考
    参考 Sabat, M., et al. 2006. Bioorg. Med. Chem. Lett. 16, 5973.
    产品信息
    CAS号 918870-43-6
    形式 Light yellow solid
    Hill配方 C₂₄H₂₆N₆O₃
    化学配方 C₂₄H₂₆N₆O₃
    Molar Mass 446.5
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    安全信息
    S相 S: 22-24/25

    Do not breathe dust.
    Avoid contact with skin and eyes.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,428206,Lck Inhibitor II - CAS 918870-43-6 - Calbiochem

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