merck millipore,默克密理博,04-465,Anti-IL-1R1 Antibody, rabbit monoclonal

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

当前位置：首页 > >Merck Millipore > 生命科学研究
生命科学研究

merck millipore,默克密理博,04-465,Anti-IL-1R1 Antibody, rabbit monoclonal
产品名称：Anti-IL-1R1 Antibody, rabbit monoclonal
产品型号：04-465
Detect IL-1R1 using this Anti-IL-1R1 Antibody, rabbit validated for use in WB.

merck millipore,默克密理博,04-465,Anti-IL-1R1 Antibody, rabbit monoclonal

产品介绍

merck millipore,默克密理博,04-465,Anti-IL-1R1 Antibody, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	WB	Rb	Purified	Monoclonal Antibody

描述
产品目录编号	04-465
品牌系列	Upstate
商名	Upstate
描述	Anti-IL-1R1 Antibody, rabbit monoclonal

产品信息
格式	Purified
演示	100 μL of rabbit monoclonal IgG in 60% storage buffer (50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 0.01% sodium azide and 0.05% BSA) and 40% glycerol.

应用
应用	Detect IL-1R1 using this Anti-IL-1R1 Antibody, rabbit validated for use in WB.
主要应用	Western Blotting

生物信息
免疫原品种	KLH-conjugated synthetic peptide encompassing residues near the N-terminus of human IL-1R type 1.
宿主	Rabbit
特异性	Recognizes a synthetic peptide encompassing residues near the N-terminus of human IL-1R type 1.
同种型	IgG
品种反应性	RatHumanMouse
抗体类型	Monoclonal Antibody
Entrez基因编号	NM_000877.2
Entrez基因汇总	The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
基因符号	D2S1473 IL1R1 IL-1R-1 IL1R P80 IL1RT1 IL1RA IL-1R-alpha CD121A IL-1RT1 p80
UniProt编号	P14778
UniProt汇总	FUNCTION: SwissProt: P14778 # Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2. SIZE: 569 amino acids; 65402 Da SUBUNIT: Binds IL1RAP. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. SIMILARITY: SwissProt: P14778 ## Belongs to the interleukin-1 receptor family. & Contains 3 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 TIR domain.

产品使用声明
质量保证	Routinely evaluated by immunoblot.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.

储存和货运信息

存储条件

2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.