merck millipore,默克密理博,407700,Interleukin-10, Human, Recombinant, S. frugiperda

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merck millipore,默克密理博,407700,Interleukin-10, Human, Recombinant, S. frugiperda
产品名称：Interleukin-10, Human, Recombinant, S. frugiperda
产品型号：407700

merck millipore,默克密理博,407700,Interleukin-10, Human, Recombinant, S. frugiperda

产品介绍

merck millipore,默克密理博,407700,Interleukin-10, Human, Recombinant, S. frugiperda

描述
概述	Recombinant, human interleukin-10 expressed in S. frugiperda insect cells. Pleiotropic cytokine that can exert either immunosuppressive or immunostimulatory effects on a variety of cell types. Potent modulator of monocyte/macrophage function. Exhibits anti-inflammatory effects by suppressing macrophage proliferation. Blocks lipopolysaccharide induction of MMP-2 and MMP-9. Known to reduce neuronal degeneration following CNS injury by blocking glutamate-induced caspase-3 activation. Human IL-10 is also active on murine cell lines.
产品目录编号	407700
品牌系列	Calbiochem®
同义词	rhIL-1αrhIL-1βrhIL-10

参考
参考	Bachis, A., et al. 2001. J. Neurosci. 21, 3104. Fortunato, S.J., et al. 2001. Obstet. Gynecol. 98, 284. Fleming, S.D., et al. 1996. J. Immunol. 156, 1143. Wang, C.Q., et al. 1996. J. Cell Physiol. 166, 305. Niro, H., et al. 1994. Int. Immunol. 6, 661. Moore, K., et al. 1993. Annu. Rev. Immunol. 11, 165. Vieira, P., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 1172.

参考

Bachis, A., et al. 2001. J. Neurosci. 21, 3104.
Fortunato, S.J., et al. 2001. Obstet. Gynecol. 98, 284.
Fleming, S.D., et al. 1996. J. Immunol. 156, 1143.
Wang, C.Q., et al. 1996. J. Cell Physiol. 166, 305.
Niro, H., et al. 1994. Int. Immunol. 6, 661.
Moore, K., et al. 1993. Annu. Rev. Immunol. 11, 165.
Vieira, P., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 1172.

产品信息
形式	Lyophilized
配方	Carrier-free.
Molar Mass	18600

生物信息
生物活性	ED₅₀ = 0.2-1 ng/ml as measured in a cell proliferation assay using a mouse mast cell line, MC/9.
纯度	≥95% by SDS-PAGE

理化信息
污染物	Endotoxin: <100 pg/μg IL-10
溶解度	Sterile H₂O

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	≤ -70°C
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze -70°C. Stock solutions are stable for up to 3 months at -70°C. Avoid freeze/thaw cycles of solutions.