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描述 概述 Recombinant, human interferon-β (IFN-β) expressed in CHO cells as a single glycosylated polypeptide containing 166 amino acids. Purified by chromatographic methods. IFN-β is a type I cytokine produced in response to exposure to viruses or double-stranded RNAs. It is also induced by other cytokines, such as TNF and IL-1. It is involved in the regulation of non-specific humoral immune responses and immune responses to viral infections, and thus exhibits anti-viral, anti-proliferative, and immunomodulating properties. The biological activity of IFN-β, unlike IFN-α, is strictly species-specific and will not be active across species. 产品目录编号 407318 品牌系列 Calbiochem®
同义词 Interferon α-2 precursor, IFN-β-1a, rHuIFN-β-1a 参考 参考 Goebel, M.U., et al. 2005. Physiol. Behav. 84, 807.
Graber, J., et al. 2005. J. Neuroimmunol. 161,169.
Mallada-Frechin, J., et al. 2005. Rev. Neurol. 40, 482.
Patten, S.B., et al. 2005. Mult. Scler. 11, 175.
Pohl, D., et al. 2005. Neurology 64, 888.
Schwid, S.R., et al. 2005. Arch. Neurol. 62, 785.产品信息 形式 Lyophilized 配方 Lyophilized from 62 mg/ml mannitol, 9.1 mg/ml human albumin, 0.9 mg/ml acetate, pH 7.0-7.2. Molar Mass 22500 生物信息 生物活性 Reported as IU/mg on a lot-specific basis using a viral resistance assay 纯度 ≥98% by SDS-PAGE 理化信息 溶解度 H₂O 储存和货运信息 货运代码 Blue Ice Only
毒性 Standard Handling
储存 -20°C
防潮 Protect from moisture
无需冷冻 No
特殊指南 Following reconstitution, refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 7 days at 4°C or for up to 4 months at -20°C. Avoid freeze/thaw cycles of solutions.
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