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描述 产品目录编号 14-554M 品牌系列 Upstate
商名 - Upstate
描述 EphB4 Protein, active, 250 µg 概述 N-terminal His6-tagged, recombinant, human EphB4, amino acids 561-end 应用 应用 Active, N-terminal His6-tagged, recombinant, human EphB4, amino acids 561-end, for use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 expressed by baculovirus in Sf21 insect cells 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_004444.4
Entrez基因汇总 Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. 基因符号 - HTK
- EPHB4
- EphB4
- TYRO11
- MYK1
- Tyro11
蛋白靶 EphB4 纯化方法 Ni2+/NTA-agarose 靶子系列 TK UniProt编号 - P54760
UniProt汇总 FUNCTION: SwissProt: P54760 # Receptor for members of the ephrin-B family. Binds to ephrin-B2. May have a role in events mediating differentiation and development.
SIZE: 987 amino acids; 108270 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Abundantly expressed in placenta and in a range of primary tissues and malignant cell lines. Expressed in fetal, but not adult, brain, and in primitive and myeloid, but not lymphoid, hematopoietic cells.
PTM: Autophosphorylated.
SIMILARITY: SwissProt: P54760 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. & Contains 2 fibronectin type-III domains. & Contains 1 protein kinase domain. & Contains 1 SAM (sterile alpha motif) domain.产品使用声明 质量保证 routinely evaluated by phosphorylation of poly (Glu, Tyr) (4:1) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C 包装信息 数量 250 µg 包装 Also available in 10 μg size (cat#14-554) and in bulk (cat# 14-554-K).
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