merck millipore,默克密理愽
  • merck millipore,默克密理博,400092,InSolution™ HIF-1 Inhibitor - CAS 934593-90-5 - Calbiochem

  • merck millipore,默克密理博,400092,InSolution™ HIF-1 Inhibitor - CAS 934593-90-5 - Calbiochem

    产品名称：InSolution™ HIF-1 Inhibitor - CAS 934593-90-5 - Calbiochem
    产品型号：400092


    merck millipore,默克密理博,400092,InSolution™ HIF-1 Inhibitor - CAS 934593-90-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,400092,InSolution™ HIF-1 Inhibitor - CAS 934593-90-5 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₆H₂₉NO₅934593-90-5
    描述
    概述 A cell-permeable amidophenolic compound that inhibits hypoxia-induced HIF-1 transcription activity (IC50 = 0.7 and 2.6 µM using AGS and Hep3B cells, respectively, in a reporter assay) by selectively blocking the hypoxia-induced accumulation of cellular HIF-1α protein, while exhibiting no apparent effect on the cellular level of HIF-1α mRNA or that of HIF-1β protein.
    产品目录编号 400092
    品牌系列 Calbiochem®
    同义词 Hypoxia-Inducible Factor-1 Inhibitor, 3-(2-(4-Adamantan-1-yl-phenoxy)-acetylamino)-4-hydroxybenzoic acid methyl ester
    参考
    参考 Naik, R., et. al. 2012. J. Med. Chem. 55, 10564.
    Lee, K., et. al. 2010. Biochem. Pharmacol. 80, 982.
    Lee, K., et al. 2007. J. Med. Chem. 50, 1675.
    产品信息
    CAS号 934593-90-5
    形式 Liquid
    配方 A 25 mM (5 mg/459 µL) solution of HIF-1 Inhibitor (Cat. No. 400083) in DMSO.
    Hill配方 C₂₆H₂₉NO₅
    化学配方 C₂₆H₂₉NO₅
    Molar Mass 435.5
    吸湿 Hygroscopic
    结构配方图像
    生物信息
    主靶 HIF-1
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    安全信息
    R相 R: 36/38

    Irritating to eyes and skin.
    S相 S: 26-36

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Irritant
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,400092,InSolution™ HIF-1 Inhibitor - CAS 934593-90-5 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,528114,PI 3-Kγ Inhibitor VII - CAS 6318-41-8 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,526526,PIM3 Kinase Inhibitor VII, M-110 - Calbiochem


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