• merck millipore,默克密理博,382184,Histone Deacetylase 8, His•Tag, Human Recombinant, S. frugiperda
  • merck millipore,默克密理博,382184,Histone Deacetylase 8, His•Tag, Human Recombinant, S. frugiperda

    产品名称:Histone Deacetylase 8, His•Tag, Human Recombinant, S. frugiperda
    产品型号:382184


    merck millipore,默克密理博,382184,Histone Deacetylase 8, His•Tag, Human Recombinant, S. frugiperda

  • 产品介绍
  • merck millipore,默克密理博,382184,Histone Deacetylase 8, His•Tag, Human Recombinant, S. frugiperda

    重要规格表

    描述
    概述 Full length, recombinant, human histone deacetylase 8 (HDAC8) fused to at the C-terminus to a His•Tag® sequence at and expressed in S. frugiperda insect cells using a baculovirus expression system. HDAC8 phosphorylated in vivo by PKA results in decreased activity, which leads to the hyperacetylation of histones H3 and H4. HDAC8 may play a role in one of the most frequent types of acute myeloid leukemia (AML). The active deacetylase is useful in the study of HDAC8 regulation and for inhibitor screening.
    产品目录编号 382184
    品牌系列 Calbiochem®
    同义词 HDAC8, Human, Recombinant
    参考
    参考 Waltregny, D., et al. 2005. FASEB J. 19, 966.
    Buggy, J.J., et al. 2000. Biochem J. 350, 199
    产品信息
    形式 Liquid
    配方 In 138 mM NaCl, 25 mM Tris-HCl, 10% glycerol, 0.05% TWEEN®-20 detergent, pH 8.0.
    Molar Mass 46400
    生物信息
    纯度 ≥90% by SDS-PAGE
    特异活性 ≥10 units/µg protein
    浓缩标签 Please refer to vial label for lot-specific concentration
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Standard Handling
    储存 ≤ -70°C
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-70°C).

    merck millipore,默克密理博,382184,Histone Deacetylase 8, His•Tag, Human Recombinant, S. frugiperda

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