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来源 纯度 HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free. Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE. 描述 产品目录编号 GF420 商名 - HumanKine®
描述 HumanKine® IL-12, Human Recombinant Xeno-Free Alternate Names - IL12
- Interleukin-12
背景信息 Interleukin 12 (IL-12) is an interleukin produced by dendritic cells, macrophages and human B-lymphoblastoid cells (NC-37) and is involved in the differentiation of naive T cells into Th1 cells or Th2 cells. IL-12 stimulates the production of interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) from T and natural killer (NK) cells and reduces IL-4 mediated suppression of IFN-γ. IL-12 can also block the formation of new blood vessels through its induction cascade and is a possible target for anti-cancer drug screening. IL-12 may play a role in autoimmunity by worsening the autoimmune response, due to its key role in induction of Th1 immune responses. 产品信息 配方 演示 Product is presented in PBS and filtered through a 0.2 micron filter before lyophilization. 生物信息 纯度 Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE. 来源 HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free. UniProt编号 - P29459
产品使用声明 质量保证 Bioactivity assay: Determined by the dose-dependent release of IFN-gamma from the human NK92 cell line in presence of 20
ng/mL rIL-2. ED50 is typically 0.1-0.5 ng/ml.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added. 包装信息 数量 10 µg
上一件merck millipore产品：merck millipore,默克密理博,382193,HMTase Inhibitor V, UNC0224 - CAS 1197196-48-7 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,506119,PhosphoDetect™ Anti-p38 MAP Kinase (pThr¹⁸⁰, pTyr¹⁸²) Rabbit pAb
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