• merck millipore,默克密理博,382193,HMTase Inhibitor V, UNC0224 - CAS 1197196-48-7 - Calbiochem
  • merck millipore,默克密理博,382193,HMTase Inhibitor V, UNC0224 - CAS 1197196-48-7 - Calbiochem

    产品名称:HMTase Inhibitor V, UNC0224 - CAS 1197196-48-7 - Calbiochem
    产品型号:382193
    The HMTase Inhibitor V, UNC0224, also referenced under CAS 1197196-48-7, controls the biological activity of HMTase. This small molecule/inhibitor is primarily used for Cell Signaling applications.

    merck millipore,默克密理博,382193,HMTase Inhibitor V, UNC0224 - CAS 1197196-48-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,382193,HMTase Inhibitor V, UNC0224 - CAS 1197196-48-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₆H₄₃N₇O₂ • H₂O1197196-48-7
    描述
    概述 A quinazolinamine compound that inhibits G9a and GLP histone H3K9 methyltransferase activity (IC50 ~50 and 54 nM, respectively) by targeting the lysine binding channel, while affecting muscarinic M2 receptor and histamine H1 receptor only at much higher concentrations (by 82% and 31%, respectively, at 1 µM) and exhibiting little activity against SET7/9, SET8/PreSET7, PRMT3, JMJD2E (IC50 >40 µM), or a panel of 30 GPCR, ion channels, and transporters (<20% inhibition at 1 µM).
    产品目录编号 382193
    品牌系列 Calbiochem®
    同义词 7-(3-Dimethylaminopropoxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine, H₂O, Histone Lysine Methyltransferase Inhibitor V, UNC0224, EHMT1/GLP Inhibitor III, EHMT2/G9a Inhibitor V
    参考
    参考 Liu, F., et al. 2010. J. Med. Chem. 53, 5844.
    Liu, F., et al. 2009. J. Med. Chem. 52, 7950.
    产品信息
    CAS号 1197196-48-7
    形式 Liquid
    Hill配方 C₂₆H₄₃N₇O₂ • H₂O
    化学配方 C₂₆H₄₃N₇O₂ • H₂O
    Molar Mass 503.7
    吸湿 Hygroscopic
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Standard Handling
    储存 ≤ -70°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,382193,HMTase Inhibitor V, UNC0224 - CAS 1197196-48-7 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,MABD10,Anti-DMP1, NT Antibody, clone 9B6.3
下一件merck millipore产品:merck millipore,默克密理博,GF420,HumanKine IL-12, Human Recombinant Xeno-Free



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