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merck millipore,默克密理博,382193,HMTase Inhibitor V, UNC0224 - CAS 1197196-48-7 - Calbiochem
产品名称:HMTase Inhibitor V, UNC0224 - CAS 1197196-48-7 - Calbiochem
产品型号:382193
The HMTase Inhibitor V, UNC0224, also referenced under CAS 1197196-48-7, controls the biological activity of HMTase. This small molecule/inhibitor is primarily used for Cell Signaling applications.
merck millipore,默克密理博,382193,HMTase Inhibitor V, UNC0224 - CAS 1197196-48-7 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₂₆H₄₃N₇O₂ • H₂O 1197196-48-7 描述 概述 A quinazolinamine compound that inhibits G9a and GLP histone H3K9 methyltransferase activity (IC50 ~50 and 54 nM, respectively) by targeting the lysine binding channel, while affecting muscarinic M2 receptor and histamine H1 receptor only at much higher concentrations (by 82% and 31%, respectively, at 1 µM) and exhibiting little activity against SET7/9, SET8/PreSET7, PRMT3, JMJD2E (IC50 >40 µM), or a panel of 30 GPCR, ion channels, and transporters (<20% inhibition at 1 µM). 产品目录编号 382193 品牌系列 Calbiochem®
同义词 7-(3-Dimethylaminopropoxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine, H₂O, Histone Lysine Methyltransferase Inhibitor V, UNC0224, EHMT1/GLP Inhibitor III, EHMT2/G9a Inhibitor V 参考 参考 Liu, F., et al. 2010. J. Med. Chem. 53, 5844.
Liu, F., et al. 2009. J. Med. Chem. 52, 7950.产品信息 CAS号 1197196-48-7 形式 Liquid Hill配方 C₂₆H₄₃N₇O₂ • H₂O 化学配方 C₂₆H₄₃N₇O₂ • H₂O Molar Mass 503.7 吸湿 Hygroscopic
结构配方图像 生物信息 纯度 ≥97% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C. 包装信息 惰性气体下包装 Packaged under inert gas
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