merck millipore,默克密理愽
  • merck millipore,默克密理博,382120,Histone Acetyltransferase Activator, CTB - CAS 451491-47-7 - Calbiochem

  • merck millipore,默克密理博,382120,Histone Acetyltransferase Activator, CTB - CAS 451491-47-7 - Calbiochem

    产品名称：Histone Acetyltransferase Activator, CTB - CAS 451491-47-7 - Calbiochem
    产品型号：382120
    The Histone Acetyltransferase Activator, CTB, also referenced under CAS 451491-47-7, modulates the biological activity of Histone. This small molecule/inhibitor is primarily used for Cell Structure ap More>>

    merck millipore,默克密理博,382120,Histone Acetyltransferase Activator, CTB - CAS 451491-47-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,382120,Histone Acetyltransferase Activator, CTB - CAS 451491-47-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆H₁₃ClF₃NO₂451491-47-7
    描述
    概述 A benzamide compound that activates the histone acetyltransferase (HAT) activity of p300/EP300/E1A binding protein 300 in a dose-dependent manner (~6-fold of basal HAT activity of recombinant human p300 toward purified HeLa core histones in the presence of 250 µM CTB). SERS spectrum indicates that CTB interacts with p300 preferentially via the amide groups of the α-helix and β-sheets, resulting in altered enzyme conformation, which presumably accounts for the increased enzymatic activity.
    产品目录编号 382120
    品牌系列 Calbiochem®
    同义词 N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-ethoxybenzamide, EP300 Activator, E1A binding protein 300 Activator
    参考
    参考 Mantelingu, K., et al. 2007. J. Phys. Chem. B 111, 4527.
    产品信息
    CAS号 451491-47-7
    形式 Off-white solid
    Hill配方 C₁₆H₁₃ClF₃NO₂
    化学配方 C₁₆H₁₃ClF₃NO₂
    Molar Mass 343.7
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,382120,Histone Acetyltransferase Activator, CTB - CAS 451491-47-7 - Calbiochem

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