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merck millipore,默克密理博,370679,Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, β-Phenyl-1,N²-etheno-8-bromo-, Rp-Isomer, Sodium Salt - CAS 172806-20-1 - Calbiochem
产品名称：Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, β-Phenyl-1,N²-etheno-8-bromo-, Rp-Isomer, Sodium Salt - CAS 172806-20-1 - Calbiochem
产品型号：370679
A metabolically-stable, competitive inhibitor of protein kinase G types 1α and 1β (Ki = 30 nM).
merck millipore,默克密理博,370679,Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, β-Phenyl-1,N²-etheno-8-bromo-, Rp-Isomer, Sodium Salt - CAS 172806-20-1 - Calbiochem
- 产品介绍
- merck millipore,默克密理博,370679,Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, β-Phenyl-1,N²-etheno-8-bromo-, Rp-Isomer, Sodium Salt - CAS 172806-20-1 - Calbiochem
重要规格表
经验配方 CAS号 C₁₈H₁₄BrN₅O₆PS · Na 172806-20-1 描述 概述 A metabolically-stable, competitive inhibitor of protein kinase G types 1α and 1β (Ki = 30 nM). Blocks cGMP-gated retinal type ion channels (IC50 = 25 µM) and the activation of purified PKA type II (Ki = 10 µM). More lipophilic and cell-permeable than Rp-8-pCPT-cGMPS (Cat. No. 370677). Note: 1 µmol = 0.56 mg. 产品目录编号 370679 品牌系列 Calbiochem®
同义词 Rp-8-Br-PET-cGMPS, Na, PKG Inhibitor VI 参考 参考 Wei, J.Y., et al. 1996. Biochemistry 35, 16815.
Butt, E., et al. 1995. Br. J. Pharmacol. 116, 3110.产品信息 CAS号 172806-20-1 具有ATP竞争性 N 声明 Sold under license of U.S. Patent 5,625,056, Patents DE 3,802,865.4, and DE 4,217,679 issued to BIOLOG LSI. 形式 Lyophilized Hill配方 C₁₈H₁₄BrN₅O₆PS · Na 化学配方 C₁₈H₁₄BrN₅O₆PS · Na Molar Mass 562.3 吸湿 Hygroscopic
可逆 N 结构配方图像 生物信息 主靶 PKG1α & 1β 主靶Ki 30 nM against PKG1α & 1β 纯度 ≥98% by HPLC 理化信息 细胞可渗透 Y 溶解度 H₂O 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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