merck millipore,默克密理愽
  • merck millipore,默克密理博,370674,Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem

  • merck millipore,默克密理博,370674,Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem

    产品名称：Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem
    产品型号：370674


    merck millipore,默克密理博,370674,Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,370674,Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem

    重要规格表

    经验配方
    C₁₀H₁₀BrN₅O₆PS · Na
    描述
    概述 A potent, cell-permeable, and metabolically stable inhibitor of protein kinase G (PKG; Ki = 4 µM). Acts as a cyclic nucleotide-gated channel agonist (EC50 = 173.5 µM). Significantly more lipophilic and membrane-permeable than cGMP or Rp-cGMPS. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Note: 5 µmol = 2.31 mg.
    产品目录编号 370674
    品牌系列 Calbiochem®
    同义词 Rp-8-Br-cGMPS, Na, PKG Inhibitor II
    参考
    参考 Wei, J.Y., et al. 1998. J. Mol. Neurosci. 10, 53.
    Nakamura, A., et al. 1996. Br. J. Pharmacol. 117, 407.
    Van Uffelen, B.E., et al. 1996. J. Leukoc. Biol. 60, 94.
    Nakazawa, M., et al. 1994. Eur. J. Pharmacol. 253, 179.
    Zhuo, M., et al. 1994. Nature 368, 635.
    产品信息
    具有ATP竞争性 N
    声明 Sold under license of Patent DE 3,802,865.4 issued to BIOLOG LSI.
    形式 Lyophilized
    Hill配方 C₁₀H₁₀BrN₅O₆PS · Na
    化学配方 C₁₀H₁₀BrN₅O₆PS · Na
    Molar Mass 462.2
    吸湿 Hygroscopic
    可逆 N
    结构配方图像
    生物信息
    主靶 PKG
    主靶Ki 4 µM against protein kinase G (PKG)
    纯度 ≥99% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

    merck millipore,默克密理博,370674,Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,47-206,MILLIPLEX MAP Jurkat T Cell Lysate: Unstimulated - Lysates/Reagents for Multiplex Assays
下一件merck millipore产品：merck millipore,默克密理博,116819,Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Chloro-, Rp-Isomer, Sodium Salt


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