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merck millipore,默克密理博,361553,GSK-3β Inhibitor XI - CAS 626604-39-5 - Calbiochem
产品名称：GSK-3β Inhibitor XI - CAS 626604-39-5 - Calbiochem
产品型号：361553
The GSK-3β Inhibitor XI, also referenced under CAS 626604-39-5, controls the biological activity of GSK-3β. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation appl More>>
merck millipore,默克密理博,361553,GSK-3β Inhibitor XI - CAS 626604-39-5 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₈H₁₅N₅O₃ 626604-39-5 描述 概述 A cell-permeable azaindolylmaleimide compound that acts as a potent, specific, and ATP-competitive inhibitor of GSK-3β (Ki = 25 nM) and minimally inhibits a panel of 79 commonly studied protein kinases, including several PKC isozymes. Shown to increase intracellular glycogen synthase activity in HEK293 cells with an EC50 of 32 nM and demonstrate metabolic stability in human liver microsomes (HLM; t1/2 > 100 min). 产品目录编号 361553 品牌系列 Calbiochem®
同义词 3-(1-(3-Hydroxypropyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-4-pyrazin-2-yl-pyrrole-2,5-dione, 7AIPM 参考 参考 Justman, Q.A., et al. 2009. Science 324, 509.
O'Neill, D.J., et al. 2004. Bioorg. Med. Chem. 12, 3167.产品信息 CAS号 626604-39-5 具有ATP竞争性 Y 形式 Orange red solid Hill配方 C₁₈H₁₅N₅O₃ 化学配方 C₁₈H₁₅N₅O₃ Molar Mass 349.3 可逆 N 结构配方图像 生物信息 主靶 Gsk-3β 主靶Ki 25 nM against GSK-3β 纯度 ≥95% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Carcinogenic / Teratogenic
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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