merck millipore,默克密理博,FCMAB178P,Milli-Mark™ Anti-CD11B-PE Antibody, clone 2LPM19c

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	FC	M	Phycoerythrin	Monoclonal Antibody

描述
产品目录编号	FCMAB178P
商名	Milli-Mark
描述	Milli-Mark™ Anti-CD11B-PE Antibody, clone 2LPM19c
Alternate Names	CD11 antigen-like family member B Integrin alpha-M Cell surface glycoprotein MAC-1 subunit alpha CR-3 alpha chain Leukocyte adhesion receptor MO1 Neutrophil adherence receptor
背景信息	CD11b is the 165 kDa α-chain of the Mac-1 complex. The molecule, also called CR3, functions as a cell surface receptor for the C3bi complement fragment. There is evidence that CD11b can bind fibrinogen in addition to C3bi (Wright,1988). Two binding sites have now been reported, one recognizing lipopolysaccharide, and the other protein ligands containing the arg-gly-asp sequence (Wright, 1989). Binding of the coagulation factor X has also been suggested as an additional receptor role of CD11b (Altieri,1988). This protein belings to a family of related heterodimeric proteins designated CD11 in the classification system for human leucocyte differentiation antigens, which shares a common β-chain with a MW of 95 kDa (CD18). Besides the C3bi receptor, this protein family contains two other members, leucocyte function associated-1 (LFA-1, C11a) antigen and p150,95 protein (CD11c) (Sanchez-Madrid,1983).

产品信息
格式	Phycoerythrin
控制	PBMCs
演示	Purified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

应用
应用	Milli-Mark Anti-CD11B-PE Antibody, clone 2LPM19c detects level of CD11B & has been published & validated for use in FC.
主要应用	Flow Cytometry

生物信息
免疫原品种	Purified iC3b receptor.
克隆	2LPM19c
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	Antibody recognizes Human CD11b antigen.
同种型	IgG1κ
品种反应性	Human
Species Reactivity Note	Tested and passed on Human.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_000623.2
纯化方法	Protein A purfied
UniProt编号	P11215

产品使用声明
质量保证	Evaluated by flow cytometry using human PBMCs
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

包装信息
数量	100 tests

merck millipore,默克密理博,FCMAB178P,Milli-Mark™ Anti-CD11B-PE Antibody, clone 2LPM19c

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