merck millipore,默克密理愽
  • merck millipore,默克密理博,349254,NS-398 - CAS 123653-11-2 - Calbiochem

  • merck millipore,默克密理博,349254,NS-398 - CAS 123653-11-2 - Calbiochem

    产品名称：NS-398 - CAS 123653-11-2 - Calbiochem
    产品型号：349254
    A cell-permeable selective inhibitor of COX-2 in vitro.

    merck millipore,默克密理博,349254,NS-398 - CAS 123653-11-2 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,349254,NS-398 - CAS 123653-11-2 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₃H₁₈N₂O₅S123653-11-2
    描述
    概述 A cell-permeable selective inhibitor of COX-2 in vitro. Inhibits sheep placental COX-2 (IC50 = 3.8 µM) while COX-1 activity is unaffected at concentrations up to 100 µM. Displays potent anti-inflammatory and analgesic activity in vivo in rat at concentrations from 0.3 to 5 mg/kg.
    产品目录编号 349254
    品牌系列 Calbiochem®
    同义词 N-(2-Cyclohexyloxy-4-nitrophenyl)methanesulfonamide
    参考
    参考 Ouellet, M., and Percival, M.D. 1995. Biochem. J. 306, 247.
    Futaki, N., et al. 1994. Prostaglandins 47, 55.
    Arai, I., et al. 1993. Res. Comm. Chem. Pathol. Pharmacol. 81, 259.
    Futaki, N., et al. 1993. Gen. Pharmacol. 24, 105.
    Futaki, N., et al. 1993. J. Pharm. Pharmacol. 45, 753.
    产品信息
    CAS号 123653-11-2
    具有ATP竞争性 N
    形式 Pale yellow solid
    Hill配方 C₁₃H₁₈N₂O₅S
    化学配方 C₁₃H₁₈N₂O₅S
    Molar Mass 314.4
    可逆 N
    结构配方图像
    生物信息
    主靶 COX-2
    主靶IC50 3.8 µM against COX-2
    纯度 ≥98% by TLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +15°C to +30°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

    merck millipore,默克密理博,349254,NS-398 - CAS 123653-11-2 - Calbiochem

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