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经验配方 CAS号 C₃₀H₃₁ClN₄O₄ 571203-78-6 描述 概述 A cell-permeable piperazinyl-quinazolinone compound that exhibits oncogene-selective lethality. Shown to bind mitochondrial volatage-dependent anion channels (VDAC) and alter its gating; rapidly induce an oxidative, non-apoptotic cell death in several human tumors harboring activating mutations in the RAS-RAF-MEK signaling (EC50 = 6.0 µM in BJ-TERT/LT/ST/RASV12 cells). 产品目录编号 329600 品牌系列 Calbiochem®
同义词 2-(1-(4-(2-(4-Chlorophenoxy)acetyl)-piperazin-1-yl)-ethyl)-3-(2-ethoxyphenyl)-3H-quinazolin-4-one 参考 参考 Yagoda, N., et al. 2007. Nature 447, 864. 产品信息 CAS号 571203-78-6 形式 White solid Hill配方 C₃₀H₃₁ClN₄O₄ 化学配方 C₃₀H₃₁ClN₄O₄ Molar Mass 547.1 结构配方图像 生物信息 纯度 ≥98% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Blue Ice Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
上一件merck millipore产品：merck millipore,默克密理博,04-322,Anti-Acetyl CoA Carboxylase 1 Antibody, rabbit monoclonal
下一件merck millipore产品：merck millipore,默克密理博,MAB2263,Anti-GluR1-NT (NT) Antibody, clone RH95
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