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merck millipore,默克密理博,344154,FPT Inhibitor III - Calbiochem
产品名称：FPT Inhibitor III - Calbiochem
产品型号：344154
The FPT Inhibitor III controls the biological activity of FPT. This small molecule/inhibitor is primarily used for Cancer applications.
merck millipore,默克密理博,344154,FPT Inhibitor III - Calbiochem
- 产品介绍
重要规格表
经验配方 C₂₃H₃₉NO₇P . Na 描述 概述 A cell-permeable prodrug ester form of farnesyltransferase (FTase) inhibitor II (Cat. No. 344152). Also inhibits Ras processing in cells (~100 µM), thereby preventing Ras-mediated transformation. Inhibits C15 and C20 protein prenylation in NIH-3T3 cells. 产品目录编号 344154 品牌系列 Calbiochem®
同义词 (E,E)-[2-Oxo-2-[[(3,7,11-trimethyl-2,6,10-dodecatrienyl)oxy]amino]ethyl]phosphonic Acid, (2,2-Dimethyl-1-oxopropoxy)methyl Ester, Na 参考 参考 Wang, D., et al. 1998. J. Biol. Chem. 273, 33027.
Manne, V., et al. 1995. Drug Development Res. 34, 121.产品信息 具有ATP竞争性 N 形式 Pale yellow solid Hill配方 C₂₃H₃₉NO₇P . Na 化学配方 C₂₃H₃₉NO₇P . Na Molar Mass 495.5 吸湿 Hygroscopic
可逆 N 结构配方图像 生物信息 主靶 FTase 主靶IC50 ~100 µM inhibiting Ras processing in cells, thereby preventing Ras-mediated transformation 纯度 ≥90% by HPLC 理化信息 细胞可渗透 Y 溶解度 H₂O 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
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