merck millipore,默克密理愽
  • merck millipore,默克密理博,681672,Wnt/β-catenin Inhibitor, Cardamonin - CAS 19309-14-9 - Calbiochem

  • merck millipore,默克密理博,681672,Wnt/β-catenin Inhibitor, Cardamonin - CAS 19309-14-9 - Calbiochem

    产品名称：Wnt/β-catenin Inhibitor, Cardamonin - CAS 19309-14-9 - Calbiochem
    产品型号：681672
    The Wnt/β-catenin Inhibitor, Cardamonin, also referenced under CAS 19309-14-9, controls the biological activity of Wnt/β-catenin. This small molecule/inhibitor is primarily used for Cancer application More>>

    merck millipore,默克密理博,681672,Wnt/β-catenin Inhibitor, Cardamonin - CAS 19309-14-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,681672,Wnt/β-catenin Inhibitor, Cardamonin - CAS 19309-14-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆H₁₄O₄19309-14-9
    描述
    概述 Cardamonin, a known 2',4'-dihydroxy-6'-methoxychalcone, was identified as an inhibitor of melanocyte differentiation, among many other pharmacology activities. Cardamonin promoted degradation of intracellular β-catenin while suppressing melanogenesis by down-regulating the expression of MITF and tyrosinase, resulting in decreased melanin content. Furthermore, it was found that cardamonin promoted the degradation of β-catenin through a GSK-3β-independent mechanism, which suggested that Siah-dependent pathway and/or a PKCα-dependent pathway, rather than a GSK-3β-dependent pathway, may mediate intracellularb-catenin degradation by cardamonin.
    产品目录编号 681672
    品牌系列 Calbiochem®
    同义词 Wnt Pathway Inhibitor VII, Cardamonin, (E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one
    产品信息
    CAS号 19309-14-9
    形式 Orange-yellow to amber solid
    Hill配方 C₁₆H₁₄O₄
    化学配方 C₁₆H₁₄O₄
    Molar Mass 270.28
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

    merck millipore,默克密理博,681672,Wnt/β-catenin Inhibitor, Cardamonin - CAS 19309-14-9 - Calbiochem

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