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merck millipore,默克密理博,124029,Akt Inhibitor XII, Isozyme-Selective, Akti-2 - Calbiochem
产品名称：Akt Inhibitor XII, Isozyme-Selective, Akti-2 - Calbiochem
产品型号：124029
The Akt Inhibitor XII, Isozyme-Selective, Akti-2 controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
merck millipore,默克密理博,124029,Akt Inhibitor XII, Isozyme-Selective, Akti-2 - Calbiochem
- 产品介绍
重要规格表
经验配方 C₃₉H₃₉N₇O₂ • 3HCl 描述 概述 A cell-permeable Akti-1/2- (Cat. No. 124018) derived allosteric inhibitor pair (1:1 regioisomeric mixture) with much improved aqueous solubility (10 mg/ml in a pH 7.4 saline) and Akt2 selectivity (IC50 = 805 nM for Akt2, >10 µM for Akt1/3, and >50 µM for PKA/PKC/SGK). The inhibition is PH domain-dependent and non-competitive with ATP. 产品目录编号 124029 品牌系列 Calbiochem®
同义词 1-((2-(4-((4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl)methyl)phenyl)-3-phenyl-6-quinoxalinyl)carbonyl)-4-methyl-piperazine, 3HCl and, 1-((3-(4-((4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl)methyl)phenyl)-2-phenyl-6-quinoxalinyl)carbonyl)-4-methyl-piperazine, 3HCl 参考 参考 Zhao, Z., et al. 2008. Bioorg. Med. Chem. Lett. 18, 49. 产品信息 形式 Yellow solid Hill配方 C₃₉H₃₉N₇O₂ • 3HCl 化学配方 C₃₉H₃₉N₇O₂ • 3HCl Molar Mass 747.2 吸湿 Hygroscopic
结构配方图像 生物信息 纯度 ≥97% by HPLC (mixture of regioisomers) 理化信息 溶解度 DMSO or H₂O 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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