merck millipore,默克密理博,341589,FGF, Acidic, Mouse, Recombinant

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merck millipore,默克密理博,341589,FGF, Acidic, Mouse, Recombinant
产品名称：FGF, Acidic, Mouse, Recombinant
产品型号：341589

merck millipore,默克密理博,341589,FGF, Acidic, Mouse, Recombinant

产品介绍

merck millipore,默克密理博,341589,FGF, Acidic, Mouse, Recombinant

重要规格表

纯度
≥95% SDS-PAGE

描述
概述	Recombinant, mouse fibroblast growth factor (FGF) acidic, consisting of amino acids 16-155 and expressed in E. coli, with an N-terminal Met. FGF acidic stimulates proliferation of all cells of mesodermal origin and many cells of ectodermal, neuroectodermal, and endodermal origin. Intracellular FGF acidic inhibits p53 activity and proapoptotic signaling, thereby enabling it to function as a survival factor.
产品目录编号	341589
品牌系列	Calbiochem®
同义词	HBGF-1

参考
参考	Guerrini, M., et al. 2007. Curr. Pharm. Des. 13, 2045. Nilsen, T., et al. 2007. J. Biol. Chem. 282, 26245. Rajalingam, D., et al. 2007. Biochemistry 46, 9225. Wesche, J., et al. 2006. J. Biol. Chem. 281, 11405. Bouleau, S., et al. 2005. Oncogene 24, 7839. Mohammadi, M., et al. 2005. Cytokine Growth Factor Rev. 16, 107. Presta, M., et al. 2005. Cytokine Growth Factor Rev. 16, 159. Robinson, C.J., et al. 2005. J. Biol. Chem. 280, 42274. Wesche, J., et al. 2005. Biochemistry 44, 6071. Wiedlocha, A., et al. 2005. Mol. Biol. Cell 16, 794. Wiedlocha, A. and V. Sorensen. 2004. Curr. Top. Microbiol. Immunol. 286, 45. Allen, B.L. and A.C. Rapraeger. 2003. J. Cell Biol. 163, 637. Galzie, Z., et al. 1997. Biochem. Cell Biol. 75, 669. Madiai, F., et al. 1996. Gene 179, 231. Imamura, T., et al. 1990. Science 249, 1567.

参考

Guerrini, M., et al. 2007. Curr. Pharm. Des. 13, 2045.
Nilsen, T., et al. 2007. J. Biol. Chem. 282, 26245.
Rajalingam, D., et al. 2007. Biochemistry 46, 9225.
Wesche, J., et al. 2006. J. Biol. Chem. 281, 11405.
Bouleau, S., et al. 2005. Oncogene 24, 7839.
Mohammadi, M., et al. 2005. Cytokine Growth Factor Rev. 16, 107.
Presta, M., et al. 2005. Cytokine Growth Factor Rev. 16, 159.
Robinson, C.J., et al. 2005. J. Biol. Chem. 280, 42274.
Wesche, J., et al. 2005. Biochemistry 44, 6071.
Wiedlocha, A., et al. 2005. Mol. Biol. Cell 16, 794.
Wiedlocha, A. and V. Sorensen. 2004. Curr. Top. Microbiol. Immunol. 286, 45.
Allen, B.L. and A.C. Rapraeger. 2003. J. Cell Biol. 163, 637.
Galzie, Z., et al. 1997. Biochem. Cell Biol. 75, 669.
Madiai, F., et al. 1996. Gene 179, 231.
Imamura, T., et al. 1990. Science 249, 1567.

产品信息
形式	Solid
配方	Lyophilized from 0.2 µm sterile-filtered solution in MOPS, Na₂SO₄, EDTA, DTT, BSA.

生物信息
生物活性	ED₅₀ = 0.05-0.25 ng/ml, in the presence of 10 µg/ml heparin, as measured in a cell proliferation assay using NR6R-3T3 mouse fibroblasts.
纯度	≥95% SDS-PAGE

理化信息
污染物	Endotoxin: <1.0 EU/µg protein

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	-20°C
无需冷冻	No
特殊指南	Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.