merck millipore,默克密理博,116814,Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, Rp-Isomer, Triethylammonium Salt - CAS 151837-09-1

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merck millipore,默克密理博,116814,Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, Rp-Isomer, Triethylammonium Salt - CAS 151837-09-1 - Calbiochem
产品名称：Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, Rp-Isomer, Triethylammonium Salt - CAS 151837-09-1 - Calbiochem
产品型号：116814
A cell-permeable and reversible inhibitor of protein kinase A (Ki = 11 µM).

merck millipore,默克密理博,116814,Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, Rp-Isomer, Triethylammonium Salt - CAS 151837-09-1 - Calbiochem

产品介绍

merck millipore,默克密理博,116814,Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, Rp-Isomer, Triethylammonium Salt - CAS 151837-09-1 - Calbiochem

重要规格表

经验配方	CAS号
C₁₀H₁₁N₅O₅PS · (CH₃CH₂)₃NH	151837-09-1

描述
概述	A cell-permeable and reversible inhibitor of protein kinase A (K_i = 11 µM). Resistant to hydrolysis by phosphodiesterases. Noncompetitive with respect to ATP.
概述	Note: 5 µmol = 2.23 mg.
产品目录编号	116814
品牌系列	Calbiochem®
同义词	Adenosine 3ʹ,5ʹ-cyclic Phosphorothioate-Rp, Rp-cAMPS, TEA, PKA Inhibitor V

参考
参考	Kaji, H., et al. 1992. Biochem. Biophys. Res. Commun. 182, 1356. Van der Kloot, W., and Branisteanu, D.D. 1992. Eur. J. Phys. 420, 336. Yokozaki, H., et al. 1992. Cancer Res. 52, 2504. Butt, E., et al. 1990. FEBS Lett. 263, 47. Dostmann, W.R., et al. 1990. J. Biol. Chem. 265, 10484. Rothermel, J.D. 1988. Biochem. J. 251, 757. Eckstein, F. 1985. Annu. Rev. Biochem. 54, 367. de Wit, R.J., et al. 1984. Eur. J. Biochem. 142, 255. O'Brian, C.A., et al. 1982. Biochemistry 21, 4371.

参考

Kaji, H., et al. 1992. Biochem. Biophys. Res. Commun. 182, 1356.
Van der Kloot, W., and Branisteanu, D.D. 1992. Eur. J. Phys. 420, 336.
Yokozaki, H., et al. 1992. Cancer Res. 52, 2504.
Butt, E., et al. 1990. FEBS Lett. 263, 47.
Dostmann, W.R., et al. 1990. J. Biol. Chem. 265, 10484.
Rothermel, J.D. 1988. Biochem. J. 251, 757.
Eckstein, F. 1985. Annu. Rev. Biochem. 54, 367.
de Wit, R.J., et al. 1984. Eur. J. Biochem. 142, 255.
O'Brian, C.A., et al. 1982. Biochemistry 21, 4371.

产品信息
CAS号	151837-09-1
具有ATP竞争性	N
形式	Crystalline solid
Hill配方	C₁₀H₁₁N₅O₅PS · (CH₃CH₂)₃NH
化学配方	C₁₀H₁₁N₅O₅PS · (CH₃CH₂)₃NH
Molar Mass	446.5
吸湿	Hygroscopic
可逆	Y
结构配方图像

生物信息
主靶	PKA
主靶K_i	11 µM against protein kinase A
纯度	≥98% by HPLC

理化信息
细胞可渗透	Y
溶解度	H₂O

储存和货运信息
货运代码	Blue Ice Only
毒性	Standard Handling
储存	-20°C
吸湿	Hygroscopic
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

merck millipore,默克密理博,116814,Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, Rp-Isomer, Triethylammonium Salt - CAS 151837-09-1 - Calbiochem

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