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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABF22 描述 Anti-NLRP1 Antibody Alternate Names - NLRP1
- NACHT, LRR and PYD domains-containing protein 1
- Caspase recruitment domain-containing protein 7
- Death effector filament-forming ced-4-like apoptosis protein
- Nucleotide-binding domain and caspase recruitment domain
背景信息 NLRP1 (NACHT, LRR and PYD domains-containing protein 1) is also known as Caspase recruitment domain-containing protein 7, Death effector filament-forming ced-4-like apoptosis protein, and Nucleotide-binding domain and caspase recruitment domain. NLRP1 forms cytoplasmic structures called death effector filaments, is known to bind ATP, and has been shown to stimulate apoptosis via activation of caspase-3. NLRP1 is widely expressed. Genetic NLRP1 abnormalities are associated with vitiligo (VTLG) and vitiligo-associated multiple autoimmune disease type 1 (VAMAS1). 产品信息 格式 Affinity Purified 控制 - THP-1 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect NLRP using this rabbit polyclonal antibody, Anti-NLRP1 Antibody validated for use in western blotting & IHC (Paraffin). 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:250-1,000 dilution from a representative lot detected NLRP1 in bone marrow (Leukemia) and human lymphoma tissue. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human NLRP1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_127497
基因符号 - NALP1
- NLRP1
- CARD7
- DEFCAP
- KIAA0926
- NAC
纯化方法 Affinity purified UniProt编号 - Q9C000
产品使用声明 质量保证 Evaluated by Western Blotting in THP-1 cell lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected NLRP1 in 10 µg of THP-1 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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