• merck millipore,默克密理博,34115,N-Ethylmaleimide - CAS 128-53-0 - Calbiochem
  • merck millipore,默克密理博,34115,N-Ethylmaleimide - CAS 128-53-0 - Calbiochem

    产品名称:N-Ethylmaleimide - CAS 128-53-0 - Calbiochem
    产品型号:34115
    Sulfhydryl alkylating reagent that inhibits H+-ATPase and suppresses the short circuit current (IC₅₀ = 22 µM) in pancreatic duct cells.

    merck millipore,默克密理博,34115,N-Ethylmaleimide - CAS 128-53-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,34115,N-Ethylmaleimide - CAS 128-53-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₆H₇NO₂128-53-0
    描述
    概述 Sulfhydryl alkylating reagent that inhibits H+-ATPase and suppresses the short circuit current (IC50 = 22 µM) in pancreatic duct cells. Inactivates NADP-dependent isocitrate dehydrogenase. Also a potent inhibitor of both Mg2+ and Ca2+/Mg2+-stimulated DNA fragmentation in rat liver nuclei. Stimulates arachidonic acid release through activation of PLA2 in endothelial cells.
    产品目录编号 34115
    品牌系列 Calbiochem®
    同义词 NEM
    参考
    参考 Huang, Y.C., et al. 1995. Arch. Biochem. Biophys. 316, 485.
    Neve, E.P.A., et al. 1995. Biochem. Pharmacol. 49, 57.
    Cain, K., et al. 1994. Biochem. Cell Biol. 72, 631.
    Banger, K.K., et al. 1993. Biochem. J. 290, 199.
    Mattingly, J.R., Jr., et al. 1993. J. Biol. Chem. 268, 3925.
    产品信息
    CAS号 128-53-0
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₆H₇NO₂
    化学配方 C₆H₇NO₂
    Molar Mass 125.1
    可逆 N
    结构配方图像
    生物信息
    主靶 H+-ATPase
    主靶IC50 22 µM in suppressing short circuit current
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 EtOH
    GHS安全信息
    RTECS UX9625000
    安全信息
    R相 R: 21-28-34-43

    Harmful in contact with skin.
    Very toxic if swallowed.
    Causes burns.
    May cause sensitization by skin contact.
    S相 S: 26-36/37/39-45

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing, gloves and eye/face protection.
    In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Corrosive
    有害材料注意事项: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
    储存 +15°C to +30°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

    merck millipore,默克密理博,34115,N-Ethylmaleimide - CAS 128-53-0 - Calbiochem

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