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merck millipore,默克密理博,MABC756,Anti-MAP3K7, clone EPR5984, Rabbit Monoclonal Antibody
产品名称:Anti-MAP3K7, clone EPR5984, Rabbit Monoclonal Antibody
产品型号:MABC756
This Anti-MAP3K7, clone EPR5984, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of MAP3K7.
merck millipore,默克密理博,MABC756,Anti-MAP3K7, clone EPR5984, Rabbit Monoclonal Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Unpurified Monoclonal Antibody 描述 产品目录编号 MABC756 描述 Anti-MAP3K7, clone EPR5984, Rabbit Monoclonal Antibody Alternate Names - Mitogen-activated protein kinase kinase kinase 7
背景信息 Mitogen-activated protein kinase kinase kinase 7, also known as Transforming growth factor-beta-activated kinase 1 (TGF-beta-activated kinase 1), and encoded by the gene name MAP3K7 or TAK1, plays an important role in the cascades of cellular responses evoked by changes in the environment. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and it controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, MAP3K7 forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. 产品信息 格式 Unpurified 演示 Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol. 应用 应用 This Anti-MAP3K7, clone EPR5984, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of MAP3K7. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50-100 dilution from a representative lot detected MAP3K7 in human brain tissue.
Produced in collaboration with Epitomics™生物信息 免疫原品种 Synthetic peptide corresponding to the C-terminus of human MAP3K7. 表位 C-terminus 克隆 EPR5984 浓缩 Please refer to lot specific datasheet. 宿主 Rabbit 同种型 IgG 品种反应性 Human Species Reactivity Note Human 抗体类型 Monoclonal Antibody 基因符号 - TAK1
- MAP3K7
纯化方法 Unpurified UniProt编号 - O43318
产品使用声明 质量保证 Evaluated by Western Blotting in K562, HeLa, and A431 cell lysates.
Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected MAP3K7 in K562, HeLa, and A431 cell lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 100 µL
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