• merck millipore,默克密理博,324833,EGFR Inhibitor III - CAS 733009-42-2 - Calbiochem
  • merck millipore,默克密理博,324833,EGFR Inhibitor III - CAS 733009-42-2 - Calbiochem

    产品名称:EGFR Inhibitor III - CAS 733009-42-2 - Calbiochem
    产品型号:324833
    The EGFR Inhibitor III, also referenced under CAS 733009-42-2, controls the biological activity of EGFR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applica More>>

    merck millipore,默克密理博,324833,EGFR Inhibitor III - CAS 733009-42-2 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,324833,EGFR Inhibitor III - CAS 733009-42-2 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆H₁₀Cl₃FN₄O733009-42-2
    描述
    概述 A cell-permeable quinazolinyl-chloroacetamide compound that selectively and irreversibly blocks EGFR autophosphorylation with no effect on the expression levels of EGFR, and suppresses leiomyoma and myometrical cell proliferation (IC50 = 0.7 µM and 1.1 µM, respectively). Shown to induce apoptosis and cell cycle arrest, and in combination with Genistein (Cat. No. 345834) completely suppress leiomyoma cell proliferation.
    产品目录编号 324833
    品牌系列 Calbiochem®
    同义词 N-(4-((3,4-Dichloro-6-fluorophenyl)amino)-quinazolin-6-yl)-2-chloroacetamide
    参考
    参考 Shushan, A., et al. 2007. Fertil. Steril. 87, 127.
    产品信息
    CAS号 733009-42-2
    具有ATP竞争性 N
    形式 Yellow solid
    Hill配方 C₁₆H₁₀Cl₃FN₄O
    化学配方 C₁₆H₁₀Cl₃FN₄O
    Molar Mass 399.6
    可逆 N
    结构配方图像
    生物信息
    主靶 EGFR
    主靶IC50 0.7 µM and 1.1 µM suppressesing leiomyoma and myometrical cell proliferation, respectively
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,324833,EGFR Inhibitor III - CAS 733009-42-2 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,05-756,Anti-Calsenilin/DREAM Antibody, clone 40A5
下一件merck millipore产品:merck millipore,默克密理博,07-1334,Anti-JunD Antibody



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