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品种反应性 主要应用 宿主 格式 抗体类型 B, H, M, R WB, ICC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 07-1334 Replaces MABE558 描述 Anti-JunD Antibody Alternate Names - transcription factor jun-D
- JunD-FL isoform
- activator protein 1
- jun D proto-oncogene
背景信息 JunD is a member of the JUN family, and a functional component of the AP1 transcription factor complex. JunD binds an AP-1 site and upon cotransfection stimulates the activity of a promoter that bears an AP-1 site. It also binds DNA as a dimer. Furthermore, JunD has been proposed to protect cells from p53-dependent senescence and apoptosis. 产品信息 格式 Affinity Purified 控制 - HeLa cell lysate
演示 Purified rabbit polyclonal containing 0.1 M Tris-glycine, pH 7.4, 0.150 mM NaCl and 0.05% sodium azide. 应用 应用 Anti-JunD Antibody is a Rabbit Polyclonal Antibody for detection of JunD also known as JunD-FL isoform, transcription factor jun-D & has been validated in ICC & WB. 主要应用 - Western Blotting
- Immunocytochemistry
应用说明 Western Blot (SNAP ID Technique):
A 1:2,000 dilution from a previous lot detected JunD using the SNAP ID analysis.
Immunocytochemistry Analysis: A 1:500 dilution from a previous lot detected JunB in TPA-treated HeLa lysates.
Immunocytochemistry Analysis:
Representative images from a previous lot.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human JunD. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes JunD. 品种反应性 BovineHumanMouseRat Species Reactivity Note Proven to react with human.
Predicted to react with mouse, rat, and cow based on 100% sequence homology.抗体类型 Polyclonal Antibody Entrez基因编号 - NP_005345
Entrez基因汇总 The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage results in the production of different isoforms. 基因符号 - AP-1
纯化方法 Affinity Purfied UniProt编号 - P17535
UniProt汇总 FUNCTION: Binds an AP-1 site and upon cotransfection stimulates the activity of a promoter that bears an AP-1 site.
SUBUNIT STRUCTURE: Binds DNA as a dimer By similarity.
SUBCELLULAR LOCATION: Nucleus.
SEQUENCE SIMILARITIES: Belongs to the bZIP family. Jun subfamily.
Contains 1 bZIP domain.
SEQUENCE CAUTION: The sequence CAA40010.1 differs from that shown. Reason: Frameshift at several positions.产品使用声明 质量保证 Evaluated by Western Blot in TPA-treated HeLa cell lysate.
Western Blot Analysis: 0.25 µg/mL of this antibody detected JunD in 10 µg of TPA-treated HeLa cell lysate. Antibody will also work in untreated HeLa cells and lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable at 2-8°C for 1 year from date of receipt. 包装信息 数量 100 µg
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