merck millipore,默克密理博,252750,Deferoxamine Mesylate - CAS 138-14-7

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Merck Millipore 默克密理愽

merck millipore,默克密理博,252750,Deferoxamine Mesylate - CAS 138-14-7 - Calbiochem

经验配方	CAS号
C₂₅H₄₈N₆O₈·CH₄O₃S	138-14-7

描述
概述	Parenteral iron chelating agent. Commonly used in therapy as a chelator of ferric iron in disorders of iron overload. Completely protects against dopamine-induced cell death. Has also been shown to interfere with hydroxyl radical formation, which mediates tissue damage in several disease states. Shows anti-proliferative effect on vascular smooth muscle cells in vitro and in vivo. Can also inhibit the oxidative chemistry of peroxynitrite by reaction of the hydroxamic acid moieties with trans-peroxynitrous acid.
产品目录编号	252750
品牌系列	Calbiochem®
同义词	Desferrioxamine Mesylate, DFOM, Iron Chelator II

参考
参考	Bergeron, R.J., et al. 1996. J. Med. Chem. 39, 1575. Ben-Shachar, D., et al. 1995. J. Neurochem. 64, 718. Denicola, A., et al. 1995. Free Radic. Biol. Med. 19, 11. Dzwigaj, S., and pererat, H., 1995. Free Radic. Res. 14, 103. Dang, S., et al. 1994. Res. Commun. Mol. Pathol. Pharmacol. 86, 43. Porreca, E., et al. 1994. Arterioscler. Thromb. 14, 299.

生物信息
纯度	92.5-100% by TLC

理化信息
溶解度	H₂O

GHS安全信息
RTECS	UG5310000

安全信息
R相	R: 22-36/37/38-40-42/43 Harmful if swallowed. Irritating to eyes, respiratory system and skin. Limited evidence of a carcinogenic effect. May cause sensitization by inhalation and skin contact.
S相	S: 22-26-36 Do not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Harmful & Carcinogenic / Teratogenic
储存	+2°C to +8°C
吸湿	Hygroscopic
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

merck millipore,默克密理博,252750,Deferoxamine Mesylate - CAS 138-14-7 - Calbiochem

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