merck millipore,默克密理博,04-212,Anti-phospho-c-Jun (Ser63) Antibody,clone Y172, rabbit monoclonal

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merck millipore,默克密理博,04-212,Anti-phospho-c-Jun (Ser63) Antibody,clone Y172, rabbit monoclonal
产品名称：Anti-phospho-c-Jun (Ser63) Antibody,clone Y172, rabbit monoclonal
产品型号：04-212
Anti-phospho-c-Jun (Ser63) Antibody, clone Y172 is an antibody against phospho-c-Jun (Ser63) for use in IC, IH, IH(P), IP & WB.

merck millipore,默克密理博,04-212,Anti-phospho-c-Jun (Ser63) Antibody,clone Y172, rabbit monoclonal

产品介绍

merck millipore,默克密理博,04-212,Anti-phospho-c-Jun (Ser63) Antibody,clone Y172, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	WB, ICC, IHC	Rb	Culture Supernatant	Monoclonal Antibody

描述
产品目录编号	04-212
品牌系列	Upstate
商名	Upstate
描述	Anti-phospho-c-Jun (Ser63) Antibody,clone Y172, rabbit monoclonal
Alternate Names	Activator protein 1 Jun activation domain binding protein Proto-oncogene c-jun V-jun avian sarcoma virus 17 oncogene homolog enhancer-binding protein AP1 jun oncogene v-jun sarcoma virus 17 oncogene homolog
背景信息	Jun is a component of the transcription factor AP-1, and can constitute AP-1 activity either as a homodimer or as a heterodimer with Fos. By contrast with Fos, Jun is expressed constitutively, and can be activated by phosphorylation of serines 63 and/or 73. These sites are targets for the SAPK1/JNK family of protein kinases, and their phosphorylation states can be monitored using antibodies specific for the phospho-epitopes. In addition, Jun is phosphorylated by GSK3 on sites which inhibit Jun activity. Since GSK3 is inactivated by Akt, the Akt pathway results in Jun activation.

产品信息
格式	Culture Supernatant
控制	Anisomycin treated NIH/3T3 cell lysate
演示	Unpurified rabbit monoclonal IgG in buffer containing 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

应用
应用	Anti-phospho-c-Jun (Ser63) Antibody, clone Y172 is an antibody against phospho-c-Jun (Ser63) for use in IC, IH, IH(P), IP & WB.
主要应用	Western Blotting Immunocytochemistry Immunohistochemistry
应用说明	Immunohistochemistry: A 1:50-100 dilution of a previous lot was used in IH. Immunoprecipitation: A 1:50 dilution of a previous lot was used in IP. Immunocytochemistry: A 1:100-200 dilution of a previous lot was used in IC.

生物信息
免疫原品种	Synthetic peptide directed against phosphoylated Ser63 of human c-Jun and surrounding amino acids.
表位	Ser63
克隆	Y172
宿主	Rabbit
特异性	This antibody recognizes phosphorylated c-Jun at and around Ser63.
同种型	IgG
品种反应性	RatHumanMouse
Species Reactivity Note	Proven to react with human, mouse and rat.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_002219.1
Entrez基因汇总	This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq]
基因符号	p39 AP-1 AP1 OTTHUMP00000010036 c-Jun
修改	Phosphorylation
UniProt编号	P05412

产品使用声明
质量保证	Routinely evaluated by Western Blot on NIH/3T3 cell lysate. Western Blot Analysis: A 1:5,000-1:10,000 dilution of this lot was used to detect Phospho c-Jun (Ser63) NIH/3T3 cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20ºC from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.