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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB3886 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Arp2 Antibody 产品信息 格式 Affinity Purified 演示 Affinity purified immunoglobulin. Liquid in 0.02M phosphate buffer, 0.25M NaCl, with 0.1% sodium azide as a preservative. 应用 应用 Anti-Arp2 Antibody is an antibody against Arp2 for use in WB. 主要应用 - Western Blotting
应用说明 Western blot: 1:1,000-1:2,000 (0.5-1.0 μg/mL).
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Synthetic peptide corresponding to amino acids 320-341 of human Arp2. The immunogen sequence is 100% identical in mouse, rat, Xenopus, and chicken. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes Arp2 (Actin-related protein 2). Arp2 belongs to the Arp2/3 complex, which, when stimulated by WASp/Scar proteins, nucleates actin polymerization from the sides of pre-existing actin filaments. The evolutionarily conserved Arp2/3 complex includes Arp2, Apr3, p41-Arc, p34-Arc, p21-Arc, p20-Arc and p16-Arc. 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_005722.2
- NM_001005386.1
Entrez基因汇总 The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene. 基因符号 - ARP2
- ACTR2
UniProt编号 - P61160
UniProt汇总 FUNCTION: SwissProt: P61160 # Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament.
SIZE: 394 amino acids; 44761 Da
SUBUNIT: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC.
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
SIMILARITY: SwissProt: P61160 ## Belongs to the actin family. ARP2 subfamily.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8ºC in undiluted aliquots for up to one year from date of receipt. 包装信息 数量 100 µg
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