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描述 产品目录编号 14-630M 品牌系列 Upstate
商名 - Upstate
描述 KDR Protein, active, 250 µg 概述 human KDR expressed by baculovirus in Sf21 insect cells 应用 应用 Active, N-terminal His6-tagged, recombinant, human KDR amino acids 790-end,
for use in Kinase Assays.主要应用 - Kinase Assay
生物信息 来源 N-terminal His6-tagged, recombinant, human KDR amino acids 790-end 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_002253.1
基因符号 - VEGFR
- KDR
- VEGFR-2
- VEGFR2
- CD309
- FLK1
蛋白靶 KDR 纯化方法 Ni2+/NTA-agarose 靶子系列 TK UniProt编号 - P35968
UniProt汇总 FUNCTION: SwissProt: P35968 # Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
SIZE: 1356 amino acids; 151527 Da
SUBUNIT: Interacts with SHB upon VEGF activation. Interacts with HIV-1 Tat.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SIMILARITY: SwissProt: P35968 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. & Contains 7 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.产品使用声明 质量保证 routinely evaluated by phosphorylation of myelin basic protein (MBP) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C 包装信息 数量 250 µg 包装 Also available in 10 μg size (cat#14-630) and in bulk (cat# 14-630-K).
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