- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,676505,VEGFR2 Kinase Inhibitor VII, SKLB1002 - Calbiochem
产品名称：VEGFR2 Kinase Inhibitor VII, SKLB1002 - Calbiochem
产品型号：676505
The VEGFR2 Kinase Inhibitor VII, SKLB1002 controls the biological activity of VEGFR2 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
merck millipore,默克密理博,676505,VEGFR2 Kinase Inhibitor VII, SKLB1002 - Calbiochem
- 产品介绍
重要规格表
经验配方 C₁₃H₁₂N₄O₂S₂ 描述 概述 A cell-permeable quinazoline that acts as a potent, ATP-binding site-targeting, VEGFR2-selective inhibitor (IC50 = 32 nM), while exhibiting much reduced or little activity against 16 other kinases. An effective antiangiogenesis agent (98% inhibition of HUVEC tube formation at 10 µM; 80% inhibition of zebrafish embryos intersegmental vessel growth at 2.5 µM) that significantly suppresses SW620- and HepG2-derived tumor growth in mice (by 72% and 63%, respectively, in 18 days; 100 mg/kg/day; i.p.) in vivo. 产品目录编号 676505 品牌系列 Calbiochem®
同义词 VEGFR Tyrosine Kinase Inhibitor XXXV, 6,7-Dimethoxy-4-(5-methyl-1,3,4-thiadiazol-2-ylthio)quinazoline, Vascular Endothelial Growth Factor Receptor 2 Kinase Inhibitor VII, SKLB1002 参考 参考 Zhang, S., et al. 2011. Clin. Cancer Res. 17, 4439. 产品信息 形式 White solid Hill配方 C₁₃H₁₂N₄O₂S₂ 化学配方 C₁₃H₁₂N₄O₂S₂ Molar Mass 320.4 结构配方图像 生物信息 纯度 ≥98% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
毒性 Regulatory Review
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
上一件merck millipore产品：merck millipore,默克密理博,70972,His•Tag AP Western Reagents
下一件merck millipore产品：merck millipore,默克密理博,AG928,β Amyloid 1-42, aβ, Y10A, TFA, recombinant human
相关产品
merck millipore,默克密理博,AG243,Midkine, recombinant human
merck millipore,默克密理博,06-1119,Anti-TLR2 Antibody
merck millipore,默克密理博,3700-OP,OmniPur DNA Extraction Buffer - Calbiochem
merck millipore,默克密理博,AP107-KC,Rabbit Anti Goat Fc (KC) - MG
merck millipore,默克密理博,70972,His•Tag AP Western Reagents
merck millipore,默克密理博,AG928,β Amyloid 1-42, aβ, Y10A, TFA, recombinant human
merck millipore,默克密理博,14-630M,KDR Protein, active, 250 µg
merck millipore,默克密理博,PP540NA-K,Mouse IgG Purified, No Azide (1gm)
merck millipore,默克密理博,12-569,Monomethyl-Histone H3 (Lys9) Peptide, biotin conjugate
