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描述 概述 Native C-reactive protein highly purified from human serum. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca2+-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer. Intended for use as a calibration standard for assays of CRP, for structural and functional studies, and as an antigen for production of antisera. Calibrated by electroimmunoassay against WHO reference standard or equivalent. No reaction in ODD and Laurell electroimmunoassay against polyvalent antiserum to normal human serum, antiserum to pooled effusion fluids and monospecific antiserum to human IgG. M.W. 23,000 (monomer); 115,000 (pentamer). 产品目录编号 236603 品牌系列 Calbiochem®
同义词 CRP 参考 参考 Paffen, E., et al. 2004. Arterioscler. Thromb. Vasc. Biol. 24, 975. 产品信息 CAS号 9007-41-4 形式 Liquid 配方 In 140 mM NaCl, 10 mM Tris, 2 mM CaCl₂, 0.1% NaN₃, pH 8.0. 生物信息 纯度 ≥99% by SDS-PAGE 来源 Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. 储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C).
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