merck millipore,默克密理愽
  • merck millipore,默克密理博,236007,COX-1 Inhibitor IV, TFAP - CAS 1011244-68-0 - Calbiochem

  • merck millipore,默克密理博,236007,COX-1 Inhibitor IV, TFAP - CAS 1011244-68-0 - Calbiochem

    产品名称：COX-1 Inhibitor IV, TFAP - CAS 1011244-68-0 - Calbiochem
    产品型号：236007
    The COX-1 Inhibitor IV, TFAP, also referenced under CAS 1011244-68-0, controls the biological activity of COX-1. This small molecule/inhibitor is primarily used for Cell Signaling applications.

    merck millipore,默克密理博,236007,COX-1 Inhibitor IV, TFAP - CAS 1011244-68-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,236007,COX-1 Inhibitor IV, TFAP - CAS 1011244-68-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₃H₁₀F₃N₃O1011244-68-0
    描述
    概述 A cell-permeable pyridinyl-benzamide compound that acts as a COX-1-selective inhibitor (IC50 = 0.80 and 210 µM against ovine COX-1 and COX-2, respectively) by targeting the enzyme's active site and displays analgesic properties in mice and rats in vivo (30 mg/kg, p.o.) without long-term cytotoxic effects (300 mg/kg in mice, daily, p.o. for 14 days). Unlike COX-2-inhibiting analgesics such as aspirin, TFAP is shown not to cause gastric damage in rats in vivo (300 mg/kg, p.o.).
    产品目录编号 236007
    品牌系列 Calbiochem®
    同义词 N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide
    参考
    参考 Kakuta, H., et al. 2008. J. Med. Chem. 51, 2400.
    产品信息
    CAS号 1011244-68-0
    形式 Off-white solid
    Hill配方 C₁₃H₁₀F₃N₃O
    化学配方 C₁₃H₁₀F₃N₃O
    Molar Mass 281.2
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    安全信息
    S相 S: 22-24/25

    Do not breathe dust.
    Avoid contact with skin and eyes.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,236007,COX-1 Inhibitor IV, TFAP - CAS 1011244-68-0 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,178196,α₁-Antichymotrypsin, Human Plasma - CAS 141176-92-3 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,BH-CTRL,Bioptechs Controller


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