• merck millipore,默克密理博,219457,Cdk Inhibitor, p35 - CAS 471270-60-7 - Calbiochem
  • merck millipore,默克密理博,219457,Cdk Inhibitor, p35 - CAS 471270-60-7 - Calbiochem

    产品名称:Cdk Inhibitor, p35 - CAS 471270-60-7 - Calbiochem
    产品型号:219457
    The Cdk Inhibitor, p35, also referenced under CAS 471270-60-7, controls the biological activity of Cdk. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicat More>>

    merck millipore,默克密理博,219457,Cdk Inhibitor, p35 - CAS 471270-60-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,219457,Cdk Inhibitor, p35 - CAS 471270-60-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₈H₂₄N₆O₂471270-60-7
    描述
    概述 An analog of Olomoucine (Cat. No. 495620) that acts as a potent inhibitor of Cdk1 (IC50 = 100 nM) and Cdk2 (IC50 = 80 nM). Also displays anti-proliferative and pro-apoptotic effects. The correlation between inhibition of Cdk1/Cdk2 and inhibition of cell proliferation suggests that the anti-proliferative effects are due, in part, to Cdk inhibition.
    产品目录编号 219457
    品牌系列 Calbiochem®
    同义词 2-(3-Hydroxypropylamino)-6-(o-hydroxybenzylamino)-9-isopropylpurine
    参考
    参考 Vermeulen, K., et al. 2002. Leukemia 16, 299.
    产品信息
    CAS号 471270-60-7
    具有ATP竞争性 N
    形式 Yellow solid
    Hill配方 C₁₈H₂₄N₆O₂
    化学配方 C₁₈H₂₄N₆O₂
    Molar Mass 356.4
    可逆 N
    结构配方图像
    生物信息
    主靶 CDK1, CDK2
    主靶IC50 100 nM, 80 nM, against Cdk1 and Cdk2, respectively
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,219457,Cdk Inhibitor, p35 - CAS 471270-60-7 - Calbiochem

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