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merck millipore,默克密理博,GF314,TNF- α Protein, Human Recombinant Animal Free
产品名称：TNF- α Protein, Human Recombinant Animal Free
产品型号：GF314
Tumor necrosis factor alpha (TNF-α), also known as cachectin & TNFSF1A, is the prototypic ligand of the TNF superfamily. Recombinant animal free human TNF-α is manufactured using all non-animal reagen More>>
merck millipore,默克密理博,GF314,TNF- α Protein, Human Recombinant Animal Free
- 产品介绍
重要规格表
来源 纯度 E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses 描述 产品目录编号 GF314 描述 TNF- α Protein, Human Recombinant Animal Free Alternate Names - TNFSF1A
- Tumor Necrosis Factor Alpha
- TNFa
- TNF-alpha
- Cachectin
背景信息 Tumor necrosis factor alpha (TNF-α), also known as cachectin and TNFSF1A, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, apoptosis, and immune system development. TNF-α is produced by a wide variety of immune and epithelial cell types. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-α is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-α also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Recombinant human TNF-α is a soluble 157 amino acid protein (17.4 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein. 产品信息 配方 演示 Product is filtered through a 0.2 micron filter before lyophilization. 应用 应用 Tumor necrosis factor alpha (TNF-α), also known as cachectin & TNFSF1A, is the prototypic ligand of the TNF superfamily. Recombinant animal free human TNF-α is manufactured using all non-animal reagents. 生物信息 纯度 Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses 来源 E. coli 交叉反应性 Cow, Monkey, Mouse, Rat, Sheep Entrez基因编号 - NM_000594.2
UniProt编号 - P01375
产品使用声明 质量保证 Bioactivity assay: The ED50 as determined by the cytolysis of murine L929 cells in the presence of Actinomyocin D is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥2 x 107 units/mg. 储存和货运信息 存储条件 Store at -20°C for up to 6 months from date of receipt. 包装信息 数量 50 µg
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